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Microbial and epidemiological study of aggressive periodontal disease in Moroccan adolescence.

Research Project

Project/Area Number 24406035
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section海外学術
Research Field Social dentistry
Research InstitutionKyushu Dental College

Principal Investigator

ANSAI TOSHIHIRO  九州歯科大学, 歯学部, 教授 (80244789)

Co-Investigator(Kenkyū-buntansha) MIYAZAKI Hideo  新潟大学, 歯学部, 教授 (00157629)
YOSHIDA Akihiro  松本歯科大学, 歯学部, 教授 (20364151)
YAMASHITA Yoshihisa  九州大学, 歯学部, 教授 (20192403)
SOH Inho  九州歯科大学, 歯学部, 講師 (10285463)
AWANO Shuji  九州歯科大学, 歯学部, 教授 (20301442)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
KeywordsAa菌 / 若年性歯周病 / 海外疫学調査 / 歯周病 / A.a菌 / 海外学術調査
Outline of Final Research Achievements

Aggressive periodontitis are specifically involved in adolescence. However, there are no comprehensive studies which clarified the environmental and genetic factors in regard to aggressive periodontitis. This epidemiological study analyzed oral status, and properties of the patients using by questionnaire (e.g. age, sex, socioeconomic status, nutrition, and so on…). In genetic studies, we analyzed the existence of A. actinomycetemcomitans JP2 in subgingival plaque and molecular anthropological studies using by mitochondrial DNA sequences from blood cells.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (12 results)

All 2015 2014 2013 2012 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) Book (3 results) Remarks (2 results)

  • [Journal Article] Proteome analysis identifies the Dpr protein of Streptococcus mutans as an important factor in the presence of early Streptococcal colonizers of tooth surfaces.2015

    • Author(s)
      Yoshida, A et al.
    • Journal Title

      PLOS ONE

      Volume: 10 Issue: 3 Pages: e0121176-e0121176

    • DOI

      10.1371/journal.pone.0121176

    • NAID

      120005845335

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Monitoring the prevalence of viable and dead cariogenic bacteria in oral specimens and in vitro biofilms by qPCR combined with propidium monoazide.2013

    • Author(s)
      Yasunaga, A., Yoshida, A., Morikawa, K., Maki, K., Nakamura, S., Soh, I., Awano, S. and Ansai, T.
    • Journal Title

      BMC Microbiology

      Volume: 13 Pages: 157-157

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quantitative discrimination of Aggregatibacter actinomycetemcomitans highly leukotoxic JP2 clone from non-JP2 clones in diagnosis of aggressive periodontitis.2012

    • Author(s)
      Yoshida A, Ennibi OK, Miyazaki H, Hoshino T, Hayashida H, Nishihara T, Awano S, Ansai T.
    • Journal Title

      BMC Infectious diseases

      Volume: 12 Issue: 1 Pages: 253-253

    • DOI

      10.1186/1471-2334-12-253

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] カリエスフリー小児からの新規抗う蝕細菌の同定2014

    • Author(s)
      中村 卓、ほか
    • Organizer
      日本口腔衛生学会
    • Place of Presentation
      熊本市
    • Year and Date
      2014-05-29 – 2014-05-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] 歯面初期定着菌と共培養時に発現するStreptococcus mutanタンパク質の解析2013

    • Author(s)
      吉田明弘、安永愛、安細敏弘
    • Organizer
      第62回日本口腔衛生学会
    • Place of Presentation
      松本
    • Related Report
      2013 Annual Research Report
  • [Presentation] Aggregatibacter actinomycetemcomitansロイコトキシン産生/非産生株の選択的定量検出法の開発2012

    • Author(s)
      吉田明弘、ほか
    • Organizer
      第61回日本口腔衛生学会総会
    • Place of Presentation
      神奈川歯科大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] Streptococcus anginosus βC-S lyaseによる組織傷害性の解析

    • Author(s)
      中村卓、吉田明弘、星野倫範、吉田康夫、藤原卓、安細敏弘
    • Organizer
      第66回日本細菌学会九州地方会総会
    • Place of Presentation
      長崎
    • Related Report
      2013 Annual Research Report
  • [Book] Oral disease and hydrogen sulfide production by oral bacteria.2013

    • Author(s)
      Yoshida, A., Niki, M., Ansai, T. and Nakayama, K.
    • Total Pages
      210
    • Publisher
      Nova Science
    • Related Report
      2013 Annual Research Report
  • [Book] DHEA in Human Health and Aging2012

    • Author(s)
      Yoshida, A., et al.
    • Total Pages
      452
    • Publisher
      CRC Press, Taylor & Francis Group LLC.
    • Related Report
      2012 Annual Research Report
  • [Book] Periodontal Diseases A Clinician's Guide2012

    • Author(s)
      Yoshida, A., et al.
    • Total Pages
      368
    • Publisher
      InTech
    • Related Report
      2012 Annual Research Report
  • [Remarks] 九州歯科大学地域健康開発歯学分野

    • URL

      http://www2.kyu-dent.ac.jp/dept/oral-health

    • Related Report
      2013 Annual Research Report
  • [Remarks]

    • URL

      http://www2.kyu-dent.ac.jp/dept/oral-health

    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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