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Research about the mechanism by which physiological exercise indicates the myocardial protection of the senior citizen.

Research Project

Project/Area Number 24500850
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

SATO Shigehito  浜松医科大学, 医学部, 教授 (30143176)

Co-Investigator(Kenkyū-buntansha) MOCHIZUKI Toshiaki  浜松医科大学, 医学部附属病院, 講師 (40293641)
三村 真一郎  浜松医科大学, 医学部附属病院, 助教 (30625471)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords一酸化窒素 / NO代謝産物 / 心筋虚血 / 高齢ラット / 運動負荷 / 高齢者の運動 / 自律神経系 / 一酸化窒素(NO) / 孤立心筋モデル / 運動療法 / 虚血・再灌流
Outline of Final Research Achievements

In retired rats, we could not find the effect of physical training on the cardiac function, and the area of infarction after ischemia/reperfusion injury. But we found the significant decrease in the body weight in trained group. Though we couldn't find the cardio protective effect of physical training, our results may be useful in researching the future study in this field. In the last year, we researched about the change of the cardiovascular system after exercise between the senior people (more than 65 years old) and non-senior people (less than 50 years old). We found the decrease in sympathetic nerve tone and systolic blood pressure after examination in both group. Moreover in cold period, we found the tissue perfusion index which couldn't be measured before examination became measurable after examination.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2014 2013

All Presentation (4 results)

  • [Presentation] A cace of an athlete with lumbar spinal canal stenosis that improved with epidural neuroplasty using racz spring guide catheter.2014

    • Author(s)
      Sano H, Natsumoto T, Kimura T, Mizuno K, Suzuki K, Igarashi H, Kato T, Taniguchi M, Makino H, Sato S
    • Organizer
      AAFPS(2nd Asian Congress on Pain)2014
    • Place of Presentation
      Taipei
    • Related Report
      2013 Research-status Report
  • [Presentation] A cace of central pain for which ECT was effective.2014

    • Author(s)
      Suzuki K, Sano H, Kimura T, Mizuno K, Kato T, Taniguchi M, Makino H, Igarashi H, Sato S
    • Organizer
      AAFPS(2nd Asian Congress on Pain)2014
    • Place of Presentation
      Taipei
    • Related Report
      2013 Research-status Report
  • [Presentation] 腰部脊柱管狭窄症による下肢痛に対してRaczカテーテルによる硬膜外神経形成術を施行した1症例.2013

    • Author(s)
      水野香織,五十嵐寛,谷口美づき,木村哲朗,石田千鶴,加藤弘美,牧野洋,佐野秀樹,加藤孝澄,佐藤重仁
    • Organizer
      日本ペインクリニック学会第47回大会
    • Place of Presentation
      さいたま市
    • Related Report
      2013 Research-status Report
  • [Presentation] Cardioprotection by therapeutic hypothermia to out-of-hospital cardiac arrest patients.2013

    • Author(s)
      Mochizuki T, Yanagi Y, Kawashima S, Sato S
    • Organizer
      NWAC2013 World Anesthesia Convention
    • Place of Presentation
      Bangkok
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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