| Project/Area Number |
24500850
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MOCHIZUKI Toshiaki 浜松医科大学, 医学部附属病院, 講師 (40293641)
三村 真一郎 浜松医科大学, 医学部附属病院, 助教 (30625471)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 一酸化窒素 / NO代謝産物 / 心筋虚血 / 高齢ラット / 運動負荷 / 高齢者の運動 / 自律神経系 / 一酸化窒素（NO） / 孤立心筋モデル / 運動療法 / 虚血・再灌流 |
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| Outline of Final Research Achievements |
In retired rats, we could not find the effect of physical training on the cardiac function, and the area of infarction after ischemia/reperfusion injury. But we found the significant decrease in the body weight in trained group. Though we couldn't find the cardio protective effect of physical training, our results may be useful in researching the future study in this field. In the last year, we researched about the change of the cardiovascular system after exercise between the senior people (more than 65 years old) and non-senior people (less than 50 years old). We found the decrease in sympathetic nerve tone and systolic blood pressure after examination in both group. Moreover in cold period, we found the tissue perfusion index which couldn't be measured before examination became measurable after examination.
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