Vascular endothelial dysfunction and hypertension in general population
Project/Area Number |
24590790
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Public health/Health science
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Research Institution | Osaka University |
Principal Investigator |
CUI Renzhe 大阪大学, 医学(系)研究科(研究院), 助教 (40375514)
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Co-Investigator(Kenkyū-buntansha) |
ISO Hiroyasu 大阪大学, 医学系研究科, 教授 (50223053)
KIYAMA Masahiko 大阪がん循環器病予防センター, 予防推進部, 部長 (10450925)
OHIRA Tetsuya 福島県立医科大学, 医学部, 教授 (50448031)
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Co-Investigator(Renkei-kenkyūsha) |
KITAMURA Akihiko 大阪大学, 医学系研究科, 準教授 (80450922)
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | FMD検査 / cGMP / 高血圧 / 血管内皮機能 / 疫学研究 / FMD検査 / cGMP |
Outline of Final Research Achievements |
This study investigated the association of flow mediated dilatation (FMD) with brachial blood pressure and central aortic pressure in general population. FMD values was inversely associated with systolic and diastolic blood pressure, central aortic pressure, and heavy drinking. Also, central aortic pressure was positively associated with ECG ST-T abnormalities and left ventricular hypertrophy independent of brachial blood pressure.
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] An association between central aortic pressure and subclinical organ damage of the heart among a general Japanese cohort: Circulatory Risk in Communities Study (CIRCS).2014
Author(s)
Cui R, Li Y, Krisztina G, Yamagishi K, Umesawa M, Imano H, Ohira T, Kiyama M, Okada T, Kitamura A, Hitsumoto S, Tanigawa T, Iso H
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Journal Title
Atherosclerosis
Volume: 232
Issue: 1
Pages: 94-98
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] An association between central aortic pressure and subclinical organ damage of the heart among a general Japanese cohort: Circulatory Risk in Communities Study (CIRCS)2014
Author(s)
Cui R, Li Y, Krisztina G, Yamagishi K, Umesawa M, Imano H, Ohira T, Kiyama M, Okada T, Kitamura A, Hitsumoto S, Tanigawa T, Iso H
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Journal Title
Atherosclerosis
Volume: 232
Pages: 94-98
Related Report
Peer Reviewed
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[Journal Article] Total and high molecular weight adiponectin levels and risk of cardiovascular disease in individuals with high blood glucose levels2013
Author(s)
Saito I, Yamagishi K, Chei CL, Cui R, Ohira T, Kitamura A, Kiyama M, Imano H, Okada T, Kato T, Hitsumoto S, Ishikawa Y, Tanigawa T, Iso H.
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Journal Title
Atherosclerosis
Volume: 229
Pages: 222-227
Related Report
Peer Reviewed
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[Journal Article] High-density lipoprotein subclasses and risk of stroke and its subtypes in Japanese population: the Circulatory Risk in Communities Study.2013
Author(s)
Chei CL, Yamagishi K, Kitamura A, Kiyama M, Imano H, Ohira T, Cui R, Tanigawa T, Sankai T, Ishikawa Y, Sato S, Hitsumoto S, Iso H
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Journal Title
Stroke
Volume: 44
Pages: 327-333
Related Report
Peer Reviewed
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[Journal Article] Risk factors for sudden cardiac death among Japanese: the Circulatory Risk in Communities Study.2012
Author(s)
Ohira T, Maruyama M, Imano H, Kitamura A, Kiyama M, Okada T, Maeda K, Yamagishi K, Noda H, Cui R, Masuda S, Kimura H, Tachikawa K, Ishikawa Y, Iso H
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Journal Title
J Hypertens
Volume: 30
Pages: 1137-1143
Related Report
Peer Reviewed
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[Presentation] Correlates of flow mediated dilatation (FMD) in general population: A cross-sectional study2014
Author(s)
Liu K, Cui R, Maruyama K, Kiyama M, Okada T, Kitamura A, Eshak ES, Umesawa M, Yamagishi K, Imano H, Ohira T, Tanigawa T, Iso H
Organizer
第24回日本疫学会学術総会
Place of Presentation
仙台市
Related Report
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