International mathematical epidemiological study for future prediction about mortality of hepatocellular carcinoma with districts and birth year
| Project/Area Number |
24590793
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Hiroshima University |
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Principal Investigator |
TANAKA Junko 広島大学, 医歯薬保健学研究院, 教授 (70155266)
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| Co-Investigator(Kenkyū-buntansha) |
KATAYAMA Keiko 広島大学, 大学院医歯薬保健学研究院, 講師 (50304415)
MATSUO Junko 広島大学, 大学院医歯薬保健学研究院, 助教 (70570232)
AKITA Tomoyuki 広島大学, 大学院医歯薬保健学研究院, 特任助教 (80609925)
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| Research Collaborator |
Michael Busch サンフランシスコ血液センター, Prof.
Miriam J Alter CDC, Dr.
Zanevskaia Liudmila Iosyphovna , Dr.
Nguyen Van Nhon , ビントン県保健局長
Do Huy Son , ベトナムのビントン県保健所長
Svay Somana カンボジア保健省
Lim Olline カンボジア保健省
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 肝炎肝癌対策 / 国際情報交換 / 感染症 / 数理疫学モデル / 肝炎ウイルス感染 / 肝癌死亡 / カンボジア / ベトナム / 衛生学 / 疫学 / 数理疫学 / カンボジア王国 / ベトナム社会主義共和国 / 肝炎ウイルス / 血清疫学調査 / 国際共同研究 / アメリカ合衆国 / ウクライナ共和国 |
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| Outline of Final Research Achievements |
We investigated prevalence of HBV and HCV infections among general population in Cambodia and Vietnam by the epidemiological surveys. Prevalence of HBsAg, anti-HCV and HCV RNA were 4.6％,5.8%, 2.3% in Cambodia and 15.3%, 3.3% and 1.8% in Vietnam. We have simulated the mortality due to hepatocellular carcinoma by the age-period-cohort (APC) model with use of sex- and age-specific mortality data during 1940 through 2010 in Japan for the purpose of validating the utility and assessing the limitation of this model. The observed HCC mortality in 2010 in males was lower than the predicted, and corresponded to 72.3% of the predicted data. This would be attributed to combined effects of medical interventions, such as antiviral treatments and screening for hepatitis viruses implemented.
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Report
(4 results)
Research Products
(55 results)
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[Journal Article] High prevalence of hepatitis B and C virus infections among adults living in Binh Thuan province, Vietnam2015
Author(s)
Do S H, Yamada H, Fujimoto M, Ohisa M, Matsuo J, Akita T, Katayama K, Van Nguyen N, Miyakawa Y, Tanaka J
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Journal Title
Hepatology Research
Volume: 45
Issue: 3
Pages: 259-68
DOI
Related Report
Peer Reviewed
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[Journal Article] Report from a Viral Hepatitis Policy Forum on implementing the WHO framework for global action on viral hepatitis in North Asia2013
Author(s)
Chen D-S, Locarnini S, Wait S, Bae SH, Chen PJ, Fung JY, Kim HS, Lu SN, Sung J, Tanaka J, Wakita T, Ward J, Wallace J
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Journal Title
Journal of Hepatology
Volume: 59(5)
Issue: 5
Pages: 1073-1080
DOI
Related Report
Peer Reviewed
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[Journal Article] Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients: a propensity score analysis2013
Author(s)
Kumada T, Toyoda H, Tada T, Kiriyama S, Tanikawa M, Hisanaga Y, Kanamori A, Niinomi T, Yasuda S, Ando Y, Yamamoto K, Tanaka J
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Journal Title
Journal of Hepatology
Volume: 58
Pages: 427-433
Related Report
Peer Reviewed
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[Journal Article] Follow up of the 987 blood donors found with hepatitis C virus infection over 9-18 years.2012
Author(s)
Matsuo J, Mizui M, Okita H, Katayama K, Aimitsu S, Sakata T, Obayashi M, Nakanishi T, Chayama K, Miyakawa Y, Yoshizawa H, Tanaka J, ( Hiroshima Hepatitis Study Group)
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Journal Title
Hepatology Research
Volume: 42
Issue: 7
Pages: 637-647
DOI
NAID
Related Report
Peer Reviewed
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[Presentation] Sero-epidemiological study on hepatitis B and C virus infection among school students in Siem Reap, Cambodia2015
Author(s)
Fujimoto M, Yamada H, Matsuoka T, Akita T, Ohisa M, Lim O, Hok S, Do S H, Goto N, Katayama K, Svay S, Tanaka J
Organizer
第25回日本疫学会学術総会
Place of Presentation
名古屋
Year and Date
2015-01-23
Related Report
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[Presentation] Sero-epidemiological study on hepatitis viral infection among school students in Cambodia2014
Author(s)
Fujimoto M, Yamada H, Akita T, Lim O, Hok S, Matsuo J, Go Y, Do H S, Goto N, Katayama K, Svay S, Tanaka J
Organizer
第3回放射線災害復興を推進するフェニックスリーダー育成プログラム国際シンポジウム
Place of Presentation
大阪
Related Report
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[Presentation] Hepatitis B and C virus infections among the general population in the South of Vietnam: seroprevalence, genotypic distribution and risk factors.2014
Author(s)
Do H S, Yamada H, Fujimoto M, Sato T, Kaishima T, Matsuoka T, Fujii T, Ohisa M, Go Y, Matsuo J, Katayama K, Nguyen V N, Tanaka J
Organizer
第3回放射線災害復興を推進するフェニックスリーダー育成プログラム国際シンポジウム
Place of Presentation
広島
Related Report
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[Presentation] Risk factors for hepatitis viral infections (HBV, HCV) among adults in Cambodia based on the sero-epidemiological study2014
Author(s)
Yamada H, Fujimoto M, Ohisa M, Lim O, Hok S, Matsuo J, Go Y, Do H S, Goto N, Katayama K, Svay S, Tanaka J
Organizer
第3回放射線災害復興を推進するフェニックスリーダー育成プログラム国際シンポジウム
Place of Presentation
広島
Related Report
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[Presentation] Study on hepatitis viral infection among school students in Cambodia2013
Author(s)
Fujimoto M, Yamada H, Akita T, Lim O, Hok S, Matsuo J, Go Y, Do H S, Goto N, Katayama K, Svay S, Tanaka J
Organizer
APASL(Asian Paciffic Association for the Study of the Liver 2013)
Place of Presentation
シンガポール
Related Report
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[Presentation] The sero-epidemiological study on hepatitis viral infections among adults in Cambodia2013
Author(s)
Yamada H, Fujimoto M, Ohisa M, Lim O, Hok S, Matsuo J, Go Y, Do H S, Toto N, Katayama K, Svay S, Tanaka J
Organizer
APASL(Asian Paciffic Association for the Study of the Liver 2013)
Place of Presentation
シンガポール
Related Report
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[Presentation] Study on hepatitis viral infection among school students in Cambodia2013
Author(s)
Fujimoto M, Yamada H, Akita T, Lim O, Hok S, Matsuo J, Go Y, Do H S, Goto N, Katayama K, Svay S, Tanaka J
Organizer
放射線災害復興を推進するフェニックスリーダー育成プログラム国際シンポジウム
Place of Presentation
広島
Related Report
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[Presentation] The Sero-epidemiological study on hepatitis viral infections among adults in Cambodia2013
Author(s)
Yamada H, Fujimoto M, Ohisa M, Lim O, Hok S, Matsuo J, Go Y, Do H S, Goto N, Katayama K, Svay S, Tanaka J
Organizer
放射線災害復興を推進するフェニックスリーダー育成プログラム国際シンポジウム
Place of Presentation
広島
Related Report
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