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The effect of acupuncture on leg blood flow and muscle sympathetic nerve activity

Research Project

Project/Area Number 24590905
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General internal medicine (including Psychosomatic medicine)
Research InstitutionKansai University of Health Sciences

Principal Investigator

KIMURA KENICHI  関西医療大学, 保健医療学部, 准教授 (50353040)

Co-Investigator(Kenkyū-buntansha) TAJIMA Fumihiro  和歌山県立医科大学, 医学部, 教授 (00227076)
ISHIDA Kazuya  和歌山県立医科大学, 医学部, 助教 (70398460)
TAKAHASHI Noriyo  大阪医科大学, 医学部, 助教 (80296714)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords鍼 / 筋交感神経活動 / 下肢血流 / 血圧
Outline of Final Research Achievements

In Experiment 1, no significant changes over time in contralateral leg blood flow were seen compared with the pre-stimulation value as a result of acupuncture to ST 36. Likewise, no significant difference was seen in a comparison of acupuncture and sham acupuncture. In Experiment 2, acupuncture to ST 36 in a resting state had no effect on muscle sympathetic nerve activity (MSNA). However, while no change in mean blood pressure was seen during acupuncture stimulation to ST 36 with sham acupuncture stimulation, a significant decrease was identified with true acupuncture. This suggests that the decrease in mean blood pressure during acupuncture to ST 36 may be not due to decreased MSNA. In Experiment 3, an increase in MSNA was seen, together with a decrease in skin temperature during local cooling, but acupuncture did not inhibit the increased MSNA response to local cooling.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (12 results)

All 2015 2014 2013 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (8 results)

  • [Journal Article] The effect of electro-acupuncture with different frequencies on muscle oxygenation in humans2015

    • Author(s)
      Kimura K, Ryujin T, Uno M, Wakayama I
    • Journal Title

      Evidence based Complementary and Alternative Medicine

      Volume: 2015 Pages: 1-6

    • DOI

      10.1155/2015/620785

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 鍼刺激や電子温灸による皮膚血流増加反応と一酸化窒素の関与2013

    • Author(s)
      木村研一, 若山育郎
    • Journal Title

      自律神経

      Volume: 50 Pages: 284-287

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of nitric oxide synthase inhibition on cutaneous vasodilation in response to acupuncture stimulation in humans2013

    • Author(s)
      Kimura K, Takeuchi H, Yuri K, Wakayama I
    • Journal Title

      Acupuncture in Med

      Volume: 31(1) Issue: 1 Pages: 74-80

    • DOI

      10.1136/acupmed-2012-010177

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Inhibition of nitric oxide synthase attenuates cutaneous vasodilation during warm moxibustion-like thermal stimulation in humans2012

    • Author(s)
      Kimura K, Takeuchi H, Yuri K, Wakayama I
    • Journal Title

      J Altern Complement Med

      Volume: 18(10) Issue: 10 Pages: 965-970

    • DOI

      10.1089/acm.2011.0433

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 鍼刺激が筋交感神経活動および循環動態に与える影響2014

    • Author(s)
      木村研一、中村健、高橋紀代、田島文博
    • Organizer
      日本自律神経学会
    • Place of Presentation
      埼玉
    • Year and Date
      2014-10-30 – 2014-10-31
    • Related Report
      2014 Annual Research Report
  • [Presentation] 鍼刺激や電子温灸による局所皮膚血流増加反応と一酸化窒素の関与 マイクロダイアリシス法による検討2014

    • Author(s)
      木村研一,竹内勇人,百合邦子,若山育郎
    • Organizer
      第31回日本サーモロジー学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-06 – 2014-06-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] 低周波鍼通電療法が筋酸素動態に及ぼす影響 周波数による比較.2014

    • Author(s)
      龍神 孝慶, 木村 研一, 坂口 俊二, 楳田 高士, 郭 哲次, 若山 育郎
    • Organizer
      第63回全日本鍼灸学会学術大会
    • Place of Presentation
      愛媛
    • Year and Date
      2014-05-16 – 2014-05-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effects of nitric oxide synthase inhibition on cutaneous vasodilation in response to acupuncture stimulation in humans2013

    • Author(s)
      Kimura K, Takeuchi H, Yuri K, Wakayama I
    • Organizer
      8th World Conference on Acupuncture
    • Place of Presentation
      Sydney, Australia
    • Related Report
      2013 Research-status Report
  • [Presentation] アイスパック時の交感神経活動と下肢血流2013

    • Author(s)
      石田和也, 中村健, 木村研一, 高橋紀代, 神埜奈美, 田島文博
    • Organizer
      第40回日本生体電気・物理刺激研究会
    • Place of Presentation
      京都
    • Related Report
      2013 Research-status Report
  • [Presentation] Inhibition of nitric oxide synthase attenuates cutaneous vasodilation during warm moxibustion-like thermal stimulation in humans.2013

    • Author(s)
      Kimura K, Takeuchi H, Yuri K, Wakayama I
    • Organizer
      Society for Acupuncture Research
    • Place of Presentation
      Michigan University
    • Related Report
      2012 Research-status Report
  • [Presentation] 鍼刺激による皮膚血管拡張反応へのNO合成酵素阻害薬の影響2012

    • Author(s)
      木村研一, 竹内勇人, 百合邦子, 若山育郎
    • Organizer
      第61回全日本鍼灸学会学術大会
    • Place of Presentation
      四日市文化会館(三重)
    • Related Report
      2012 Research-status Report
  • [Presentation] 電子温灸による皮膚血管拡張反応と一酸化窒素(NO)の関与2012

    • Author(s)
      木村研一, 若山育郎
    • Organizer
      第65回日本自律神経学会総会
    • Place of Presentation
      都市センターホテル(東京)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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