| Project/Area Number |
24591309
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurology
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
UEHARA Toshiyuki 独立行政法人国立循環器病研究センター, 病院, 医長 (60505098)
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| Co-Investigator(Kenkyū-buntansha) |
TOYODA Kazunori 国立循環器病研究センター, 病院, 部長 (50275450)
MINEMATSU Kazuo 国立循環器病研究センター, 病院, 副院長 (60200094)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 一過性脳虚血発作 / 脳卒中 / 画像検査 / 救急 / 予後 |
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| Outline of Final Research Achievements |
First, we elucidated the factors associated with the time from symptom onset to arrival at a stroke center in patients with TIA using data from a multicenter, retrospective study. Second, we demonstrated that the presence of Fluid-attenuated inversion recovery hyperintensity (FVH) early after symptom onset may help to diagnosis TIA, to identify the potential mechanisms of TIA and to predict recurrence risk after a TIA. Finally, we reported that patients with TIA should be cautiously manage, even when neither large-artery disease or atrial fibrillation are identified by urgent workup, and that clinical findings as motor lacunar symptom or high admission blood pressure, besides diffusion-weighted imaging findings, may be helpful to predict early stroke in such patients.
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