Establishment of clinical analysis method for higher brain dysfunctions using ASL-MRI
| Project/Area Number |
24591774
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Research Institute, International Medical Center of Japan (2014)
Saga University (2012-2013) |
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Principal Investigator |
NOGUCHI Tomoyuki 独立行政法人国立国際医療研究センター, その他部局等, その他 (40380448)
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| Co-Investigator(Kenkyū-buntansha) |
浅見 豊子 佐賀大学, 医学部, 准教授 (20222599)
入江 裕之 佐賀大学, 医学部, 教授 (50284493)
西原 正志 佐賀大学, 医学部, 助教 (50516557)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | ASL / MRI / 脳機能画像 / 高次脳機能障害 / もやもや病 / 髄膜脳炎 / 脳出血 / 脳血流 / ASL-MRI / 被殻出血 / モヤモヤ病 / 被殼出血 / 急性髄膜脳炎 |
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| Outline of Final Research Achievements |
Higher brain dysfunctions such as decreased cognitive function, aphasia or memory impairment cause daily life disability or executive function impairment, which leads difficulty to have work opportunities or return to uneventful life because of excessive burden. This fact has drawn considerable attention as one of social issues. PET or SPECT as conventional brain function nuclear medicine examinations cannot be frequently performed in all patients because of expensive examinations costs and limited spread of equipments. ASL-MRI is one of MRI imaging methods measuring cerebral blood flow non-invasively. We explored the utility of ASL-MRI as an alternative imaging methods for evaluating higher brain dysfunctions.
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Report
(4 results)
Research Products
(36 results)
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[Journal Article] Basal Ganglia Cerebral Microbleeds and Global Cognitive Function: The Kashima Scan Study.2014
Author(s)
Yakushiji Y, Noguchi T, Charidimou A, Eriguchi M, Nishihara M, Hara M, Nanri Y, Horikawa E, Nishiyama M, Werring DJ, Hara H.
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Journal Title
J Stroke Cerebrovasc Dis.
Volume: 24
Issue: 2
Pages: 431-439
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] CT-gastrography for early gastric cancer visualized by Wall-Carving technique; Value of portal phase contrast-enhanced MDCT2013
Author(s)
Kitano I, Noguchi T, Mizuguchi M, Nishihara M, Hara Y, Azama S, Yamaguchi K, Hirai T, Takase Y, Liu L, Noshiro H, Fujimoto K, Irie H
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Journal Title
Fukuoka Acta Med.
Volume: 104
Pages: 89-98
NAID
Related Report
Peer Reviewed
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[Journal Article] Distributional impact of brain microbleeds on global cognitive function in adults without neurological disorder.2012
Author(s)
Yakushiji Y, Noguchi T, Hara M, Nishihara M, Eriguchi M, Nanri Y, Nishiyama M, Hirotsu T, Nakajima J, Kuroda Y, Hara H
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Journal Title
Stroke
Volume: 43
Issue: 7
Pages: 1800-1805
DOI
Related Report
Peer Reviewed
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