Development of breast cancer risk prediction quantitative algorithms aiming at personalized medical check-up for high-risk Japanese women

• Project/Area Number: 24591915
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General surgery
• Research Institution: Yokohama City University
• Principal Investigator: CHISHIMA Takashi 横浜市立大学, 医学(系)研究科(研究院), 客員准教授 (70438141)
• Co-Investigator(Kenkyū-buntansha): ISHIKAWA Takashi 東京医科大学, 医学部, 教授 (80275049) ; SUGAE Sadatoshi 横浜市立大学, 医学部, 助教 (60644490) ; NARUI Kazutaka 横浜市立大学, 市民総合医療センター, 助教 (70468172) ; YAMADA Michiyo 横浜市立大学, 医学研究科, 客員研究員 (10328437)
• Research Collaborator: Tonellato Peter J. Harvard Medical School, Department of Biomedical Informatics
• Project Period (FY): 2012-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 国際情報交換 / 乳癌罹患リスク / リスク予測 / リスク因子解析

Outline of Final Research Achievements

We aim to create a Japanese model of risk assessment for breast cancer for further accuracy in breast medical checkup and efficacy in earlier detection of breast cancer, and conducted an investigation by questionnaires for Japanese women in fifteen medical institutions. A database of 3975 participants was created. We have been investigating breast cancer risk factors and correlation between them, and will continue to work on developing a breast cancer risk assessment model for Japanese women.

Research Products

• [Presentation] 進む乳がんの個別化治療と乳房再建 (2013)
  • Author(s): 石川孝
  • Organizer: 横浜市立大学エクステンション講座
  • Place of Presentation: 横浜市立大学（神奈川県横浜市）
  • Invited