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Development of real-time surgical assisted systems using multi-dimensional medical image and optical technique of deep visualization

Research Project

Project/Area Number 24592104
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Thoracic surgery
Research InstitutionSt. Marianna University School of Medicine

Principal Investigator

SAJI HISASHI  聖マリアンナ医科大学, 医学部, 准教授 (60420965)

Co-Investigator(Kenkyū-buntansha) IKEDA NORIHIKO  東京医科大学, 医学部, 教授 (70246205)
SHIMADA YOSHIHISA  東京医科大学, 医学部, 助教 (00459497)
YOSHIDA KOICHI  東京医科大学, 医学部, 助教 (00424490)
HAGIWARA MASARU  東京医科大学, 医学部, 助教 (90338806)
KATO YASUFUMI  東京医科大学, 医学部, 講師 (70424489)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords肺外科 / 手術シミュレーション / 手術ナビゲーション / 多次元医用画像 / 低侵襲手術 / シミュレーション / ナビゲーション / 術中ナビゲーション / 呼吸器外科手術 / 国際情報交換
Outline of Final Research Achievements

Development of safe and less-invasive surgery are warrant in the field of thoracic surgery, because of early small sized lung cancer increasing due to spread of CT survey and elderly lung cancer patients due to the aging society in Japan. In this study, we have developed a new preoperative simulation and intraoperative navigation assisted surgical systems using multi-dimensional medical image. In future studies, we will apply these results to realize practical and universal systems.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (38 results)

All 2016 2015 2014 2013 Other

All Journal Article (22 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 22 results,  Open Access: 10 results,  Acknowledgement Compliant: 3 results) Presentation (15 results) (of which Invited: 5 results) Book (1 results)

  • [Journal Article] Three-dimensional multidetector computed tomography may aid preoperative planning of the transmanubrial osteomuscular-sparing approach to completely resect superior sulcus tumor2015

    • Author(s)
      Saji H, Kato Y, Shimada Y, Kudo Y, Hagiwara M, Matsubayashi J, Nagao T, Ikeda
    • Journal Title

      Gen Thorac Cardiovasc Surg

      Volume: 63 Issue: 11 Pages: 627-31

    • DOI

      10.1007/s11748-013-0368-4

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Standardized Uptake Values in the Primary Lesions of Non-Small-Cell Lung Cancer in FDG-PET/CT Can Predict Regional Lymph Node Metastases.2015

    • Author(s)
      Nakamura H, Saji H, Marushima H, Kimura H, Tagaya R, Kurimoto N, Hoshikawa M, Takagi M.
    • Journal Title

      Ann Surg Oncol.

      Volume: -

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Survival of a surgical series of lung cancer patients with synchronous multiple ground-glass opacities, and the management of their residual lesions.2015

    • Author(s)
      Shimada Y, Saji H, Otani K, Maehara S, Maeda J, Yoshida K, Kato Y, Hagiwara M, Kakihana M, Kajiwara N, Ohira T, Akata S, Ikeda N.
    • Journal Title

      Lung Cancer

      Volume: 88 Issue: 2 Pages: 174-180

    • DOI

      10.1016/j.lungcan.2015.02.016

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Close association of IASLC/ATS/ERS lung adenocarcinoma subtypes with2015

    • Author(s)
      Nakamura H, Saji H, Shinmyo T, Tagaya R, Kurimoto N, Koizumi H, Takagi M.
    • Journal Title

      Lung Cancer

      Volume: 87 Issue: 1 Pages: 28-33

    • DOI

      10.1016/j.lungcan.2014.11.010

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of IASLC/ATS/ERS Histologic Subtypes of Lung Adenocarcinoma With Epidermal Growth Factor Receptor Mutations in 320 Resected Cases.2015

    • Author(s)
      Nakamura H, Saji H, Shinmyo T, Tagaya R, Kurimoto N, Koizumi H, Takagi M.
    • Journal Title

      Clin Lung Cancer

      Volume: 16 Issue: 3 Pages: 209-215

    • DOI

      10.1016/j.cllc.2014.10.004

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impact of Intraoperative Blood Loss on Long-Term Survival after Lung Cancer Resection2015

    • Author(s)
      Nakamura H, Saji H, Kurimoto N, Shinmyo T, Tagaya R.
    • Journal Title

      Annals of Thoracic and Cardiovascular Surgery

      Volume: 21 Issue: 1 Pages: 18-23

    • DOI

      10.5761/atcs.oa.13-00312

    • NAID

      130003396768

    • ISSN
      1341-1098, 2186-1005
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Correlation between whole tumor size and solid component size on high-resolution computed tomography in the prediction of the degree of pathologic malignancy and the prognostic outcome in primary lung adenocarcinoma.2014

    • Author(s)
      Saji H, Matsubayashi J, Akata S, Shimada Y, Kato Y, Kudo Y, Nagao T, Park J, Kakihana M, Kajiwara N, Ohira T, Ikeda N.
    • Journal Title

      Acta Radiol.

      Volume: -

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] High-quality 3-dimensional image simulation for pulmonary lobectomy and segmentectomy: results of preoperative assessment of pulmonary vessels and short-term surgical outcomes in consecutive patients undergoing video-assisted thoracic surgery2014

    • Author(s)
      Hagiwara M, Shimada Y, Kato Y, Nawa K, Makino Y, Furumoto H, Akata S, Kakihana M, Kajiwara N, Ohira T, Saji H, Ikeda N.
    • Journal Title

      Eur J Cardiothorac Surg

      Volume: 46 Issue: 6 Pages: 120-126

    • DOI

      10.1093/ejcts/ezu375

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Three-dimensional multidetector computed tomography may aid preoperative planning of the transmanubrial osteomuscular-sparing approach to completely resect superior sulcus tumor.2014

    • Author(s)
      Saji H, Kato Y, Shimada Y, Kudo Y, Hagiwara M, Matsubayashi J, Nagao T, Ikeda N.
    • Journal Title

      Gen Thorac Cardiovasc Surg.

      Volume: -

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Worldwide trend of increasing primary adenocarcinoma of the lung.2014

    • Author(s)
      Nakamura H, Saji H.
    • Journal Title

      Surg Today

      Volume: 44 Issue: 6 Pages: 1004-1021

    • DOI

      10.1007/s00595-013-0636-z

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Three-dimensional multidetector computed tomography may aid preoperative planning of the transmanubrial osteomuscular-sparing approach to completely resect superior sulcus tumor.2014

    • Author(s)
      Saji H, Kato Y, Shimada Y, Kudo Y, Hagiwara M, Matsubayashi J, Nagao T, Ikeda N
    • Journal Title

      General thoracic and cardiovascular surgery

      Volume: Epub ahead

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Impact of Intraoperative Blood Loss on Long-Term Survival after Lung Cancer Resection.2014

    • Author(s)
      Nakamura H, Saji H, Kurimoto N, Shinmyo T, Tagaya R
    • Journal Title

      Ann Thorac Cardiovasc Surg

      Volume: Epub ahead of print

    • NAID

      130003396768

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Cavernous hemangioma of the first rib.2013

    • Author(s)
      Imai K, Saji H, Ikeda N
    • Journal Title

      Asian cardiovascular & thoracic annals

      Volume: 21 Issue: 4 Pages: 488-489

    • DOI

      10.1177/0218492312457924

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Cancer stem cell-related marker expression in lung adenocarcinoma and relevance of histologic subtypes based on IASLC/ATS/ERS classification.2013

    • Author(s)
      Shimada Y, Saji H, Nomura M, Matsubayashi J, Yoshida K, Kakihana M, Kajiwara N, Ohira T, Ikeda N
    • Journal Title

      OncoTargets and therapy

      Volume: 6 Pages: 1597-1604

    • DOI

      10.2147/ott.s52353

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A proposal for combination of total number and anatomical location of involved lymph nodes for nodal classification in non-small cell lung cancer2013

    • Author(s)
      Saji H, Tsuboi M, Shimada Y, Kato Y, Yoshida K, Nomura M, Matsubayashi J, Nagao T, Kakihana M, Usuda J, Kajiwara N, Ohira T, Ikeda N
    • Journal Title

      Chest

      Volume: 143 Issue: 6 Pages: 1618-1625

    • DOI

      10.1378/chest.12-0750

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Prognostic Factors and the Significance of Treatment After Recurrence in Completely Resected Stage I Non-small Cell Lung Cancer.2013

    • Author(s)
      Shimada Y, Saji H, Yoshida K, Kakihana M, Honda H, Nomura M, Usuda J, Kajiwara N, Ohira T, Ikeda N
    • Journal Title

      Chest

      Volume: 143 Issue: 6 Pages: 1626-1634

    • DOI

      10.1378/chest.12-1717

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Virtual segmentectomy based on high-quality three-dimensional lung modelling from computed tomography images.2013

    • Author(s)
      Saji H, Inoue T, Kato Y, Shimada Y, Hagiwara M, Kudo Y, Akata S, Ikeda N
    • Journal Title

      Interact Cardiovasc Thorac Surg

      Volume: 17 Issue: 2 Pages: 227-232

    • DOI

      10.1093/icvts/ivt120

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Recent advances in video-assisted thoracoscopic surgery for lung cancer.2013

    • Author(s)
      Ikeda N, Saji H, Hagiwara M, Ohira T, Usuda J, Kajiwara N
    • Journal Title

      Asian J Endosc Surg

      Volume: 6 Issue: 1 Pages: 9-13

    • DOI

      10.1111/ases.12013

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Three Dimensional Computed Tomography Lung Modeling is Useful in Simulation and Navigation of Lung Cancer Surgery.2013

    • Author(s)
      Ikeda N, Yoshimura A, Hagiwara M, Akata S, Saji H
    • Journal Title

      Ann Thorac Cardiovasc Surg

      Volume: 19 Pages: 1-5

    • NAID

      10031176182

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Virtual segmentectomy based on high-quality three-dimensional lung modelling from2013

    • Author(s)
      Saji H, Inoue T, Kato Y, Shimada Y, Hagiwara M, Kudo Y, Akata S, Ikeda N.
    • Journal Title

      Interact Cardiovasc Thorac Surg.

      Volume: in press

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Three Dimensional Computed Tomography Lung Modeling is Useful in Simulation and2013

    • Author(s)
      Ikeda N, Yoshimura A, Hagiwara M, Akata S, Saji H.
    • Journal Title

      Ann Thorac Cardiovasc Surg.

      Volume: 20 Pages: 1-5

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Recent advances in video-assisted thoracoscopic surgery for lung cancer.2013

    • Author(s)
      Ikeda N, Saji H, Hagiwara M, Ohira T, Usuda J, Kajiwara N.
    • Journal Title

      Asian J Endosc Surg.

      Volume: 6 Pages: 9-13

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 新生児期に呼吸障害を来したCCAMに対して嚢胞切除を先行し二期的に残肺右上葉切除を施行し根治し得た1例2015

    • Author(s)
      大山 慧、佐治 久、新明卓夫、多賀谷理恵、栗本典昭、北川博昭、中村治彦
    • Organizer
      第167回日本胸部外科学会関東甲信越地方会
    • Place of Presentation
      東京ステーションコンファレンス(東京都千代田区)
    • Year and Date
      2015-03-14
    • Related Report
      2014 Research-status Report
  • [Presentation] I 呼吸器外科領域でのVINCETの活用2015

    • Author(s)
      佐治 久
    • Organizer
      富士フィルムメディカルセミナーin横浜
    • Place of Presentation
      コンカード横浜セミナー会場(神奈川県横浜市)
    • Year and Date
      2015-02-22
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 局所進行肺癌にて術前3D画像シミュレーションにより安全に治癒切除した術前導入後右中下葉+S3区域切除術2014

    • Author(s)
      佐治 久、多賀谷理恵、新明卓夫、栗本典昭、中村治彦
    • Organizer
      第55回日本肺癌学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-11-16
    • Related Report
      2014 Research-status Report
  • [Presentation] Virtual segmentectomy: preoperative simulation of segmentectomy using 3D-MDCT lung modeling2014

    • Author(s)
      Hisashi Saji, Norihiko Ikeda*, Haruhiko Nakamura
    • Organizer
      2014 IASLC Asia Pasific Lung Cancer Conference
    • Place of Presentation
      Shangri-La Hotel, Kuala Lumpur
    • Year and Date
      2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 新生児期に呼吸障害を来したCCAMに対して嚢胞切除を先行し二期的に残肺右上葉切除を施行し根治し得た1例2014

    • Author(s)
      佐治 久
    • Organizer
      第7回神奈川呼吸器外科研究会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-10-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 根治的化学放射線治療後遺残局所進行肺腺癌に術前術中高画質3D画像マネージメントにより安全に治癒切除したsalvage手術2014

    • Author(s)
      佐治 久、新明卓夫、多賀谷理恵、栗本典昭、中村治彦、池田徳彦
    • Organizer
      第67回日本胸部外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2014-10-02
    • Related Report
      2014 Research-status Report
  • [Presentation] 呼吸器外科領域における高精度3D画像支援システムによる術前シミュレーション、術中ナビゲーション手術の現状と将来展望2014

    • Author(s)
      佐治 久、萩原 優、加藤靖文、梶原直央、中村治彦、池田徳彦
    • Organizer
      第39回日本外科系連合学会学術集会
    • Place of Presentation
      日本教育会館(東京都千代田区)
    • Year and Date
      2014-06-20
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 3DMDCTシミュレーションを併用し根治的化学療法後に安全に完全切除した局所進行肺扁平上皮癌の左上葉切除術2014

    • Author(s)
      佐治 久、安藤幸二、新明卓夫、多賀谷理恵、栗本典昭、中村治彦
    • Organizer
      第31回日本呼吸器外科学会
    • Place of Presentation
      ホテル日航東京(東京都港区)
    • Year and Date
      2014-05-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Virtual segmentectomy: Preoperative simulation of segmentectomy using 3D-MDCT reconstraction software2014

    • Author(s)
      Hisashi Saji
    • Organizer
      18th WCBIP/WCBE World Congress
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-04-15
    • Related Report
      2014 Research-status Report
  • [Presentation] 外科医が日常利用できる手術シミュレーションソフト~実際の利用と有効例~2013

    • Author(s)
      佐治 久
    • Organizer
      第30回日本呼吸器外科学会総会
    • Place of Presentation
      名古屋国際会議場
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 呼吸器外科領域におけるシミュレーション、ナビゲーションの現状と将来展望-次世代低侵襲手術の構築に向けて-2013

    • Author(s)
      佐治 久、萩原優、吉田浩一、加藤靖文、石角太一郎、垣花昌俊、 臼田実男、梶原直央、大平達夫、池田徳彦
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 肺癌発見から手術シミュレーション ~容易にできる手術リハーサル~

    • Author(s)
      佐治 久
    • Organizer
      第29回日本呼吸器外科学会総会
    • Place of Presentation
      秋田キャッスルホテル
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 肺区域切除術のpits and falls – Virtual Segmentecotmyによる術前シミュレーションの重要性

    • Author(s)
      佐治 久、加藤靖文、岩崎賢太郎、吉田浩一、萩原 優、垣花昌俊、臼田実男、梶原直央、大平達夫、池田徳彦
    • Organizer
      第29回日本呼吸器外科学会総会
    • Place of Presentation
      秋田キャッスルホテル
    • Related Report
      2012 Research-status Report
  • [Presentation] 右肺尖部前壁浸潤肺癌に対して術前導入化学放射線治療後、 術後上肢運動制限を考慮した 前方アプローチによる完全切除術

    • Author(s)
      佐治 久、加藤靖文、岩崎賢太郎、垣花昌俊、臼田実男、梶原直央、大平達夫、池田徳彦
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      ホテルニューオータニ幕張
    • Related Report
      2012 Research-status Report
  • [Presentation] 呼吸器外科領域における高精度3D画像支援システムによる 術前シミュレーション、術中ナビゲーションサージャリーの 現状と将来展望

    • Author(s)
      佐治 久、加藤靖文、岩崎賢太郎、井上達哉、吉田浩一、萩原 優、垣花昌俊、臼田実男、梶原直央、大平達夫、池田徳彦
    • Organizer
      第65回日本胸部外科学会定期学術集会
    • Place of Presentation
      福岡国際会議場
    • Related Report
      2012 Research-status Report
  • [Book] EBM呼吸器疾患の治療2016-2017 ロボット手術は、呼吸器外科領域で使われるか?2016

    • Author(s)
      佐治 久、丸島秀樹、中村治彦
    • Total Pages
      495
    • Publisher
      中外医学社
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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