| Project/Area Number |
24592140
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Osaka City University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKAMI Toshihiro 大阪市立大学, 大学院医学研究科, 准教授 (20305626)
ADACHI Yoshiaki 金沢工業大学, 先端電子技術応用研究所, 教授 (80308585)
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| Co-Investigator(Renkei-kenkyūsha) |
OYAMA Daisuke 金沢工業大学, 先端電子技術応用研究所, 講師 (60569888)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 超低磁場MRI / 脳磁図 / SQUID / MEG / 小動物 / 脳磁場 / 低磁場MRI |
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| Outline of Final Research Achievements |
The purpose of this study is to perform a basic experiment aiming clinical application of ultra-low magnetic field MRI, and further to evaluate the potential of performance improvement and its fusion of micro magnetoencephalography(MEG). In micro MEG, hardware improvements, such as reducing the distance between brain surface and sensor coil and strengthening of the shield, led to successful be clearly detect the magnetic signal from the small rat brain. In vitro, the ultra-low field MRI could detect different T1 relaxation times for tumor cells (glioma and renal cell carcinoma). In vivo, it was able to capture 2D images of rat brain. But it did not lead to obtain sufficient spatial resolution for the 3D image.
To assess independently micro MEG and ultra-low field MRI, we were able to promote the study of fusion device development to the previous step.
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