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Assessment of neuropathic pain after spinal cord injury

Research Project

Project/Area Number 24592216
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionNational Hospital Organization Murayama Medical Center

Principal Investigator

Nagoshi Narihito  独立行政法人国立病院機構村山医療センター(臨床研究部), その他部局等, 研究員 (10383837)

Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords脊髄損傷 / 神経障害性疼痛
Outline of Final Research Achievements

Neuropathic pain (NP) after spinal cord injury (SCI) tends to be hard to treat, and its heterogeneous properties make it difficult to identify and characterize. This study was conducted to assess the characteristics of SCI-related NP in detail.
This study included 72 patients who were seen at our hospital in 2012 and 2013 and who had sustained SCI at least 3 months before enrollment. The patients completed the Neuropathic Pain Symptom Inventory (NPSI) and the Short Form (SF)-36 Health Inventory. Paresthesia/dysesthesia was the most common subtype of NP after SCI. With regard to location, below-level superficial NP was significantly more intense than at-level pain. Patients who underwent surgery showed significantly less evoked pain compared with patients with non-surgery. Patients reported significantly more severe pain if >1 year had elapsed after the SCI. Among the SF-36 subitems, NP correlated significantly with bodily pain, general health and mental health.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2015 2014 2013 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (6 results)

  • [Journal Article] Factors contributing to improvement of syringomyelia after foramen magnum decompression for Chiari type I malformation2014

    • Author(s)
      Narihito Nagoshi, Akio Iwanami, Yoshiaki Toyama, Masaya Nakamura
    • Journal Title

      Journal of Orthopaedic Science

      Volume: Epub Issue: 3 Pages: 418-423

    • DOI

      10.1007/s00776-014-0555-x

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Neuropathic pain and its relationship with quality of life in 72 patients with spinal cord injury2015

    • Author(s)
      Narihito Nagoshi, Masaya Nakamura
    • Organizer
      Global Spine Congress 2015
    • Place of Presentation
      ブエノスアイレス
    • Year and Date
      2015-05-20 – 2015-05-23
    • Related Report
      2014 Research-status Report
  • [Presentation] Characteristics of neuropathic pain after chronic spinal cord injury2014

    • Author(s)
      Narihito Nagoshi, Masaya Nakamura
    • Organizer
      The 36th International Symposium of the Groupe de recherche sur le système nerveux central
    • Place of Presentation
      モントリオール
    • Year and Date
      2014-05-12 – 2014-05-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 化膿性脊椎炎に対する前方固定術の手術成績2013

    • Author(s)
      名越慈人,塩田匡宣,町田正文,竹光正和,金子慎二郎,八木満,藤吉兼浩,飯塚慎吾,三宅敦,長谷川淳
    • Organizer
      第42回日本脊椎脊髄病学会
    • Place of Presentation
      沖縄
    • Related Report
      2013 Research-status Report
  • [Presentation] 慢性期脊髄損傷における神経障害性疼痛の評価2013

    • Author(s)
      名越慈人,藤吉兼浩,金子慎二郎,久保田麻由子,朝妻孝仁,中村雅也
    • Organizer
      第48回日本脊髄障害医学会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] Chiari奇形に伴う脊髄空洞症に対する大後頭孔減圧術の手術成績2013

    • Author(s)
      名越慈人,岩波明生,松本守雄,戸山芳昭,中村雅也
    • Organizer
      第48回日本脊髄障害医学会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 慢性期脊髄損傷における神経障害性疼痛の評価

    • Author(s)
      名越慈人、藤吉兼浩、金子慎二郎、塩田匡宜、町田正文、中村雅也
    • Organizer
      第47回日本脊髄障害医学会
    • Place of Presentation
      静岡県コンベンションアーツセンター
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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