| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
To establish novel bedside monitoring methods for consciousness, memory and pain during anesthesia, we observed brain activities(BA) by magnetoencephalography (MEG), because MEG results are easily applied to electroencephalography (EEG). First, we observed BA during spontaneous sleeping, and found the foci of spindle, theta and delta waves. These data are available to develop the new EEG monitoring methods for consciousness in the future, but we could not observe BA under general anesthesia, because the ethics committee did not allow the experiment. Second, we tried to find the specific changes of BA by memory formation or recollection. We found some changes related to memory, while these changes were not specific,. Third, we observed the changes caused by pain. We used harmless ice pack as pain stimulator and found pain-specific changes in the amygdala, hypocampus, insula and anterior cingulate gyrus. Some of these BA would contribute to establishment of pain monitoring system.
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