• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Immunolocalization of aquaporin1 on the interfaces between tissues with different physical properties

Research Project

Project/Area Number 24592761
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Morphological basic dentistry
Research InstitutionNiigata University

Principal Investigator

KAWANO Yoshiro  新潟大学, 医歯学系, 助教 (60303129)

Co-Investigator(Kenkyū-buntansha) MAEDA Takeyasu  新潟大学, 医歯学系, 教授 (40183941)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsアクアポリン / 歯根膜 / 歯槽骨 / セメント質 / 運動器 / 密性結合組 / 密生結合組織
Outline of Final Research Achievements

Aquaporin1 (AQP1) is a water channel protein previously identified in red blood cells and water transporting epithelia. The interfaces between tissues with different physical properties seem to be a harsh environment for the cells because of the continuous mechanical stresses caused by body action. In this study, AQP1 was found in specific cells on the interfaces between tissues which have different properties. These AQP1 positive cells on the interfaces showed poor cytoskeletons, and have big cell surface to cell volume ratios, and seem to belong to new cellular categories (different tissue connecting cells). In odontgenic cells, acellular cementblasts and alveolar bone surface cells express AQP1. It is suggested that AQP1 expressed in those stromal cells are involved in the movement of the cellular water molecules across the plasma membranes, when accompanying cellular deformations and movements, rather than water transportation.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results)

  • [Journal Article] Effect of the antineoplastic agent busulfan on rat molar root development2014

    • Author(s)
      T.Mitomi, Y kawano, S. Kinoshita-Kawano
    • Journal Title

      Archives of Oral Biology

      Volume: 1 Pages: 47-59

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] effect of the antineoplastic agent busulfan on rat molar root development2014

    • Author(s)
      T. Mitomi, Y Kawano, S. Kinoshita-Kawano
    • Journal Title

      Archives of Oral Biology

      Volume: 59 Pages: 47-59

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] アルキル化抗腫瘍薬によるラット歯根形成障害 根尖部における経日的変化2014

    • Author(s)
      三富智恵,河野芳朗,河野承子,松山順子,坂井幸子,佐野富子
    • Organizer
      第52回日本小児歯科学会大会
    • Place of Presentation
      東京
    • Year and Date
      2014-05-16 – 2014-05-17
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi