Development of a high-performance nanobiological interface control method for bioactive surface modification of hydroxyapatite with UV/ozone
Project/Area Number |
24592915
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Prosthetic dentistry
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Research Institution | Hiroshima University |
Principal Investigator |
ABE Yasuhiko 広島大学, 医歯薬保健学研究院, 准教授 (00253097)
|
Co-Investigator(Kenkyū-buntansha) |
HIRATA Isao 広島大学, 大学院医歯薬保健学研究院, 助教 (40346507)
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 生体材料 / セラミックス / ナノバイオ / 表面・界面物性 / アパタイト / 紫外線 |
Outline of Final Research Achievements |
The purpose of this study was to evaluate the effect of UV/ozone treatment on hydroxyapatite and establish the high-performance nanobiological interface control method for bioactive surface modification of hydroxyapatite. The 5-minute UV/ozone treatment could validate for the surface decontamination, the improvement and 7-day maintenance of wettability, and the acceleration of the adhesion and proliferation of MC3T3-E1 cells. Therefore, the UV/ozone treatment for the interface control between hydroxyapatite and bone was developed.
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Report
(4 results)
Research Products
(4 results)
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[Journal Article] Bioactive surface modification of hydroxyapatite2013
Author(s)
Abe, Y., Okazaki, Y., Hiasa, K., Yasuda, K., Nogami, K. Mizumachi, W. and Hirata, I.
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Journal Title
BioMed Research International
Volume: 2013
Pages: 626452-626452
DOI
Related Report
Peer Reviewed
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