Design on the surface properties of nano carbon materials, and evaluation of interaction between bioactive compounds: for application of functional biomaterials

• Project/Area Number: 24592947
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Hokkaido University
• Principal Investigator: ABE Shigeaki 北海道大学, 歯学研究科(研究院), 助教 (40374566)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 生体適合性 / ナノカーボン材料 / ナノカーボンマテリアル / 生態適合性 / カーボンナノチューブ / フラーレン / 体内動態 / ナノ粒子

Outline of Final Research Achievements

In this study, nano carbon materials such as fullerene or carbon nanotube were modified of their surface properties based on chemical modification reaction. The obtained several types of nano carbons were investigated on the interactions between biomaterials such as proteins depending on their surface properties. Their biodistribution and biocompatibility were estimated. The obtained functional groups on the surface can allow to secondary modification for applications such as drug driveller or bioimaging by emission. A Newly direct bioimaging method without any chemical modification was also succeeded based on Raman spectroscopy.

Research Products

• [Journal Article] Effect of remaining dentin thickness on microtensile bond strength of current adhesive systems (2015)
  • Author(s): S. Ting, F. Pan, J. Fu , S. Kakuda, S. Hoshika, T. Ikeda, Y. Nakaoki, S. Abe, Y. Yohida H. Sano
  • Journal Title: Dental Materials Journal Volume: 34 Issue: 2 Pages: 181-188
  • DOI: 10.4012/dmj.2014-130
  • NAID: 130005062409
  • ISSN: 0287-4547, 1881-1361
  • Peer Reviewed
• [Journal Article] Firm attachment of carboxylated multi-walled carbon nanotubes onto an amino-functionalized glass surface through ionic interaction (2015)
  • Author(s): Y. Konno, S. Abe, T. Takada
  • Journal Title: TANSO Volume: 2015 Issue: 266 Pages: 7-10
  • DOI: 10.7209/tanso.2015.7
  • NAID: 130004812845
  • ISSN: 0371-5345, 1884-5495
  • Peer Reviewed
• [Journal Article] Scanning Electron Microscope Observation of Carbon Nanotubes with Room Temperature Ionic Liquids: Effect of Their Hydrophilicities. (2015)
  • Author(s): A. Hyono, S. Abe, K. Kawai, T. Yonezawa
  • Journal Title: Journal of Nanoscience and Nanotechnology Volume: in press
  • Peer Reviewed
• [Journal Article] Cytocompatibility on HeLa cells under several nano-sized ceramics particles exposure. (2015)
  • Author(s): E. Seitoku, S. Abe, T. Kusaka, S. Inoue, H. Sano Y. Yoshida
  • Journal Title: Journal of Nanoscience and Nanotechnology Volume: in press
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Visualizing preparation using asymmetrical choline-like ionic liquids for SEM observation of non-conductive biological samples (2014)
  • Author(s): S. Abe, A. Hyono, K. Kawai, and T. Yonezawa
  • Journal Title: J. Nanoscience and Nanotechnology Volume: 14 Issue: 3 Pages: 2620-2623
  • DOI: 10.1166/jnn.2014.8629
  • Peer Reviewed
• [Journal Article] Preparation and biocompatibilities of luminescent europium-doped yttria and titania nanoparticles (2014)
  • Author(s): S. Abe, Y. Hamba, A. Hyono, S. Yamagata, M. Uo, J. Iida, T. Kiba, A. Murayama, T. Akasaka, F. Watari
  • Journal Title: Journal of the Ceramic Society of Japan Volume: 122 Issue: 1423 Pages: 216-221
  • DOI: 10.2109/jcersj2.122.216
  • NAID: 130004480234
  • ISSN: 1348-6535, 1882-0743
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Photophysical properties and biocopatibility of photoluminescent Y2O3:Eu nanoparticles in PMMA matrix. (2014)
  • Author(s): S. Abe, Y. Hamba, N. Iwadera, S. Yamagata, Y. Yawaka, M. Uo, J.-i. Iida, T. Kiba, A. Murayama F. Watari
  • Journal Title: Journal of Nanoscience and Nanotechnology Volume: 14 Issue: 4 Pages: 2891-2894
  • DOI: 10.1166/jnn.2014.8596
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Influence of surface properties on SEM observation for carbon nanotubes with pretreatment using Room Temperature Ionic Liquids. (2014)
  • Author(s): S. Abe, A. Hyono, T. Yonezawa
  • Journal Title: Journal of Solution Chemistry Volume: 43 Issue: 9-10 Pages: 1645-1654
  • DOI: 10.1007/s10953-014-0230-z
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Simple and Rapid Conductive Preparation of Wet Biological Samples for SEM Observation: Use of an Asymmetrical Choline-like Room Temperature Ionic Liquid as a Visualizing Agent (2014)
  • Author(s): S. Abe, A. Hyono, K. Kawai, K. Nakamura, Y. Yawaka, Y. Yoshida, T. Yonezawa
  • Journal Title: Nano Biomedicine Volume: 6 Issue: 1 Pages: 41-46
  • DOI: 10.11344/nano.6.41
  • NAID: 130004679869
  • ISSN: 1883-5198, 2185-4734
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Solvent Stripping Dynamics of Lithium ion solvated by ethylene carbonates: A direct ab-initio molecular (AIMD) Study (2014)
  • Author(s): H. Tachikawa, S. Abe
  • Journal Title: ELECTROCHIMICA ACTA Volume: 120 Pages: 57-64
  • DOI: 10.1016/j.electacta.2013.12.054
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Polyglycero1-coated nanodiamond as a macrophage-evading Platform for selective drug delivery in cancer cells (2014)
  • Author(s): L. Zhao, Y. Xu, S, Abe, T. Akasaka, T. Watari, T. Kimura, N. Komatsu, X, Chen
  • Journal Title: Biomaterials Volume: 35(20) Issue: 20 Pages: 5393-5406
  • DOI: 10.1016/j.biomaterials.2014.03.041
  • Peer Reviewed
• [Journal Article] Platinum on Nanodiamond : A Promising Prodrug Conjugated with Stealth Polyglycerol, Targeting peptide, and Acid-Responsive Antitumor Drug (2014)
  • Author(s): L. Zhao, Y, Xu, H. Qin, S. Abe, T. Akasaka, T. Chano, F. Watari, T. Kimura, N. Komatsu, X, Chen
  • Journal Title: Adv Funct Mater. Volume: (印刷中) Issue: 34 Pages: 5348-5357
  • DOI: 10.1002/adfm.201304298
  • Peer Reviewed
• [Journal Article] SEM observation of the live morphology of human red blood cells under high vacuum conditions using a novel RTIL. (2014)
  • Author(s): A. Hyono, T. Yonezawa, K. Kawai, S. Abe, M. Fujihara, H. Azuma, S. Wakamoto
  • Journal Title: Surface and Interface Analysis Volume: 46 Issue: 6 Pages: 425-428
  • DOI: 10.1002/sia.5471
  • Peer Reviewed
• [Journal Article] Interaction of multi-walled carbon nanotubes with water-soluble proteins: effect of sidewall carboxylation. (2014)
  • Author(s): T. Takada, R. Kurosaki, Y. Konno, S. Abe
  • Journal Title: Journal of Nanoscience and Nanotechnology Volume: 14 Issue: 4 Pages: 3216-3220
  • DOI: 10.1166/jnn.2014.8590
  • Peer Reviewed
• [Journal Article] Bone enhancing effect of titanium-binding proteins isolated from bovine bone and implanted into rat calvaria with titanium scaffold (2014)
  • Author(s): Yoshinori Kuboki, Toshitake Furusawa, Masaaki Sato, Yongkun Sun, Hidero Unuma, Shigeaki Abe, Ryuichi Fujisawa, Tsukasa Akasaka, Fumio Watari, Hiroko Takita, Rachel Sammons
  • Journal Title: Biomedical Materials and Engineering Volume: Vol.24, Number3 Issue: 3 Pages: 1539-1548
  • DOI: 10.3233/bme-140958
  • Peer Reviewed
• [Journal Article] Scanning electron microscope observation of nano carbon materials with imidazolium-type room temperature ionic liquids (2013)
  • Author(s): S. Abe, A. Hyono, K. Nakayama, T. Takada, and T. Yonezawa
  • Journal Title: Japanese J. Applied Physics Volume: 52 Issue: 1S Pages: 01AH02-01AH02
  • DOI: 10.7567/jjap.52.01ah02
  • NAID: 210000141788
  • Peer Reviewed
• [Journal Article] Photophysical Properties of Self-assembled Cyanine-dye Dimmer Formation Assisted by Cyclodextrin Inclusion Complexation (2013)
  • Author(s): Shigeaki Abe, Takashi Hirota, Takayuki Kiba, Naoyuki Miyakawa, Fumio Watari, Akihiro Murayama, Shin-Ichiro Sato
  • Journal Title: Mol. Cryst. Liq. Cryst. Volume: 579 Issue: 1 Pages: 22-29
  • DOI: 10.1080/15421406.2013.804799
  • Peer Reviewed
• [Journal Article] An evaluation of fluorescent orthodontic adhesives containing Eu-doped ZnO at room temperature (2013)
  • Author(s): S. Yamagata, H. Iwasaki, Y. Hamba, K. Nakanishi, N. Ushijima, S. Abe, T. Akasaka, F. Watari, and J. Iida
  • Journal Title: Nano Biomedicine Volume: 5 Pages: 31-38
  • NAID: 130004679855
  • Peer Reviewed
• [Journal Article] Biocompatibility and biodistribution of several nano-sized ceramics particles (2013)
  • Author(s): S. Abe, Y. Hamba, N. Iwadera, T. Akasaka, S. Yamagata, Y. Yawaka, J. Iida, M. Uo, T. Yonezawa, F. Watari
  • Journal Title: Key Engineerings and Materials Volume: 529-530 Pages: 625-629
  • DOI: 10.4028/www.scientific.net/kem.529-530.625
• [Journal Article] Influence of micro-/nano- particles on osteoblast-like cells: A static and time lapse observation (2013)
  • Author(s): N. Iwadera, S. Abe, T. Akasaka, Y. Yawaka, and F. Watari
  • Journal Title: Key Engineerings and Materials Volume: 529-530 Pages: 374-378
  • DOI: 10.4028/www.scientific.net/kem.529-530.374
• [Journal Article] Murine Macrophage RAW264.7 Cells Response for the Carbon Nanotubes Immobilized on Substrate (2013)
  • Author(s): Tsukasa Akasaka
  • Journal Title: Key Engineering Materials Volume: 529-530 Pages: 379-384
  • DOI: 10.4028/www.scientific.net/kem.529-530.379
  • Peer Reviewed
• [Journal Article] Photophysical properties and biocopatibility of photoluminescent Y2O3:Eu nanoparticles in PMMA matrix (2013)
  • Author(s): S. Abe, Y. Hamba, N. Iwadera, S. Yamagata, Y. Yawaka, M. Uo, J.-i. Iida, T. Kiba, A. Murayama and F. Watari
  • Journal Title: J. Nanoscience and Nanotechnology Volume: -
  • Peer Reviewed
• [Journal Article] Visualizing preparation using asymmetrical choline-like ionic liquids for SEM observation of non-conductive biological samples (2013)
  • Author(s): S. Abe, A. Hyono, K. Kawai and T. Yonezawa
  • Journal Title: J. Nanoscience and Nanotechnology Volume: -
  • Peer Reviewed
• [Journal Article] Interaction of multi-walled carbon nanotubes with water-soluble proteins: effect of sidewall carboxylation (2013)
  • Author(s): T. Takada, R. Kurosaki, Y. Konno, and S. Abe
  • Journal Title: J. Nanoscience and Nanotechnology Volume: -
  • Peer Reviewed
• [Journal Article] Investigation of biodistribution behavior of platinum particles in mice: Correlation between inductively coupled plasma - atomic emission spectroscopy and X-ray scanning analytical microscopy (2012)
  • Author(s): S. Abe, C. Koyama, M. Mutoh, T. Akasaka, M Uo, and F. Watari
  • Journal Title: Applied Surface Science Volume: 262 Pages: 125-128
  • DOI: 10.1016/j.apsusc.2012.03.080
  • Peer Reviewed
• [Journal Article] Morphology, size distribution and elemental composition of several dental debris (2012)
  • Author(s): S. Abe, N. Iwadera, M. Esaki, K.-I. Aoyama, T. Akasaka, M Uo, M. Morita, Y. Yawaka, and F. Watari
  • Journal Title: Applied Surface Science Volume: 262 Pages: 248-252
  • DOI: 10.1016/j.apsusc.2012.07.126
  • Peer Reviewed
• [Journal Article] Biodistribution of water-soluble Carbon Nanotubes in mice and its biocompatibility (2012)
  • Author(s): S.Abe, S.Itoh, D.Hayashi, T.Kobayashi, T.i Kiba, T.Akasaka, M.Uo, Y.Yawaka, S.Sato, F.Watari, T.Takada
  • Journal Title: J.Nanoscience and Nanotechnology Volume: 12 Issue: 1 Pages: 700-706
  • DOI: 10.1166/jnn.2012.5391
  • Peer Reviewed
• [Journal Article] A Density Functional Theory Study of Interaction of Fluorinated Ethylene Carbonate with a Graphene Surface (2012)
  • Author(s): S. Abe, F. Watari, and H. Tachikawa
  • Journal Title: Jpn. J. Appl. Phys. Volume: 51 Issue: 10S Pages: 10NE34-10NE34
  • DOI: 10.1143/jjap.51.10ne34
  • NAID: 210000141536
  • Peer Reviewed
• [Journal Article] A novel approach for direct observation of biodistribution of water-soluble carbon nanotubes in mice (2012)
  • Author(s): S. Abe, A. Hyono, F. Watari, D. Hayashi, and T. Takada
  • Journal Title: Nano Biomedicine Volume: 4
  • NAID: 130004679849
  • Peer Reviewed
• [Journal Article] Comparison of Biodistribution and Biocompatibility of Gelatin-Coated Copper Nanoparticles and Naked Copper Oxide Nanoparticles (2012)
  • Author(s): S. Abe, N. Iwadera, T. Narushima, Y. Uchida, M. Uo, T. Akasaka, Y. Yawaka, F. Watari, T. Yonezawa
  • Journal Title: e-Journal of Surface Science and Nanotechnology Volume: 10 Issue: 0 Pages: 33-37
  • DOI: 10.1380/ejssnt.2012.33
  • NAID: 130004438789
  • ISSN: 1348-0391
  • Peer Reviewed
• [Journal Article] Morphology and Photophysical Properties of One-Dimensional Arrayed Porphyrin Aggregates Assisted by Cyclodextrin Inclusion Complexation (2012)
  • Author(s): Shigeaki Abe, Hirohisa Kobayashi, Takayuki Kiba, Fumio Watari, Shin-ichiro Sato
  • Journal Title: Molecular Crystals and Liquid Crystals Volume: 566 Issue: 1 Pages: 151-157
  • DOI: 10.1080/15421406.2012.701879
  • Peer Reviewed
• [Journal Article] Interaction of Ethylene Carbonate and Graphene Chip : Density Functional Theory Study (2012)
  • Author(s): S.Abe, F.Watari, H.Tachikawa
  • Journal Title: Japanese J.Applied Physics Volume: 51 Issue: 1S Pages: 33-38
  • DOI: 10.1143/jjap.51.01ah07
  • NAID: 210000140087
  • Peer Reviewed
• [Journal Article] Carbonate ion induced calcification using biomimetic enzymes with active reaction center of carbonc anhydrase (2012)
  • Author(s): S. Abe, M. Yohda, A. Nishiyama, M. Nakatani, Y. Fujii, A. Kusuhara, E. Yamatoya, T. Ishida, T. Akasaka, M. Uo, F. Watari, D. Hayashi, and T. Takada
  • Journal Title: Nano Biomedicine Volume: 4
  • NAID: 130004679838
  • Peer Reviewed
• [Journal Article] Conductivity preparation by choline lactate ethanol solution for SEM observation: Both hard and soft tissues in living matter (2012)
  • Author(s): S. Abe, A. Hyono, Y. Machida, F. Watari, and T. Yonezawa
  • Journal Title: Nano Biomedicine Volume: 4
  • Peer Reviewed
• [Journal Article] Influence of surface properties for SEM observation of carbon nanotubes pretreated with Room Temperature Ionic Liquids
  • Author(s): S. Abe, A. Hyono, and T. Yonezawa
  • Journal Title: J. Solution Chemistry Volume: 999999999999999999999999999999 Pages: 999999999999999-999999999999999
  • Peer Reviewed
• [Presentation] Surface Modification Effect of Photoluminescent Ceramics Nanoparticles on their biocompatibility (2014)
  • Author(s): S. Abe, N. Kiyama, T. Kiba, A. Murayama, J. Iida, Y. Yoshida
  • Organizer: ICNME 2014
  • Place of Presentation: Kobe International Conference Center (Kobe, JAPAN)
  • Year and Date: 2014-12-17 – 2014-12-18
• [Presentation] Cytocompatibility of several nano-sized metal oxide particles (2014)
  • Author(s): S. Abe, E. Seitoku, H. Sano, and Y. Yoshida
  • Organizer: AsiaNANO 2014
  • Place of Presentation: Ramada Plaza Jeju Hotel (Jeju, KOREA)
  • Year and Date: 2014-10-26 – 2014-10-28
• [Presentation] イオン液体によるタンパク質保存液の試作：タンパク質の常温長期安定化 (2014)
  • Author(s): 阿部 薫明, 金子恒太郎, 河合功治, 赤坂司, 吉田 靖弘
  • Organizer: 第64回日本歯科理工学会
  • Place of Presentation: アステールプラザ（広島県・広島市中区）
  • Year and Date: 2014-10-04 – 2014-10-05
• [Presentation] Study of a solubility and long-term stability of several proteins in room temperature ionic liquids for a novel protein stock solution (2014)
  • Author(s): S. Abe, A. Hyono, N. Kaneko, K. Kaneko, K. Kawai, and Y. Yoshida
  • Organizer: 第52回日本生物物理学会
  • Place of Presentation: 札幌コンベンションセンター（北海道・札幌市白石区）
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] Preparation of higher order fullerene C60 aggregate “C60 nanowhisker”: In vivo and in silico study of C60-C60 interaction (2014)
  • Author(s): S. Abe, K. Yanai, I. Mukai, Y. Yoshida, and S. Sato
  • Organizer: NanoKorea 2014
  • Place of Presentation: COEX (Seoul, KOREA)
  • Year and Date: 2014-07-02 – 2014-07-04
• [Presentation] Study of a solubility and long-term stability of several proteins in room temperature ionic liquids for a novel protein stock solution (2014)
  • Author(s): S. Abe, A. Hyono, K. Kawai, K. Kaneko,and A. Yashita
  • Organizer: 第14回日本蛋白質科学会年会
  • Place of Presentation: 横浜マリンメッセ（神奈川県・横浜市中区）
  • Year and Date: 2014-06-25 – 2014-06-27
• [Presentation] セラミックナノ粒子の細胞刺激性の検討 (2014)
  • Author(s): 阿部薫明、岩寺信喜、半場悠介、山方 秀一、赤坂司、八若保孝、飯田順一郎、亘理文夫、古月文志
  • Organizer: 第63回日本歯科理工学会
  • Place of Presentation: タワーホール船堀（東京都江戸川区）
  • Year and Date: 2014-04-12 – 2014-04-13
• [Presentation] 有機・無機ナノマテリアルの生体への影響と体内動態の可視化 (2013)
  • Author(s): 阿部薫明, 岩寺信喜, 半場悠介, 赤坂司, 山方秀一, 八若保孝, 飯田順一郎, 高田知哉, 米澤徹, 宇尾基弘, 亘理文夫
  • Organizer: 第7回ナノ・バイオメディカル学会
  • Place of Presentation: 京都テルサ（京都）
• [Presentation] グラフェン表面上でのエチレンカーボネート誘導体の拡散挙動に関する理論的研究 (2013)
  • Author(s): 阿部薫明, 亘理文夫, 田地川浩人
  • Organizer: 化学系学協会北海道支部2013年冬季研究発表会
  • Place of Presentation: 北海道大学（札幌）
• [Presentation] カーボンナノチューブと生体関連物質との相互作用：in vitroとin silicoによる検討 (2012)
  • Author(s): 阿部薫明, 小峰梨果, 石川紘佑, 赤坂司, 亘理文夫, 田地川浩人
  • Organizer: 第59回日本歯科理工学会学術講演会
  • Place of Presentation: あわぎんホール（徳島）
• [Presentation] イオン液体を用いたナノカーボン物質の微細構造の観察 (2012)
  • Author(s): 阿部薫明, 兵野篤, 亘理文夫, 米澤徹
  • Organizer: 日本顕微鏡学会第68回学術講演会
  • Place of Presentation: 福岡国際会議場（福岡）
• [Presentation] Bidistribution and biocompatibility of nano-sized materials: An in vivo and in vitro study (2012)
  • Author(s): S. Abe, N. Iwadera, A. Sasaki, S. Itoh, T. Narushima, Y. Uchida, T. Akasaka, M. Uo, Y. Yawaka, T. Yonezawa, F. Watari
  • Organizer: 9th World Biomaterial Congress 2012
  • Place of Presentation: International Conference Center (PRC)
• [Presentation] 有機・無機マイクロ・ナノ物質の体内動態の追跡とその生体への影響 (2012)
  • Author(s): 阿部薫明, 岩寺信喜, 伊藤佐智子, 佐々木朗子, 石川紘佑, 赤坂司, 八若保孝, 宇尾基弘, 久保木芳徳, 林大輔, 高田知哉, 内田由樹, 成島隆, 米澤徹, 亘理文夫
  • Organizer: 第6回ナノ・バイオメディカル学会
  • Place of Presentation: 産業技術総合研究所（筑波）
• [Presentation] Controlled calcification using biomimetic enzymes with zinc coordinated compound: A carbonate ion induced calcification (2012)
  • Author(s): S.Abe, M. Yohda, Y. Fujii, E. Yamatoya, T. Ishida, T. Akasaka, F. Watari, M. Uo, D. Hayashi, T. Takada
  • Organizer: 19th International SPACC Symposium
  • Place of Presentation: Hokkaido University (Sapporo)
• [Presentation] Photophysical properties of self-assembled cyanine-dye aggregates formation assisted by cyclodextrin inclusion complexation (2012)
  • Author(s): S. Abe, T. Kiba, T Hirota, N. Miyakawa, F. Watari, A. Murayama, S. Sato
  • Organizer: KJF2012
  • Place of Presentation: Tohoku University (Sendai)
• [Presentation] Biodistribution and biocompatibility of water-soluble carbon nanotubes (2012)
  • Author(s): 阿部薫明, 伊藤佐智子, 小林宏寿, 木場隆之, 赤坂司, 八若保孝, 佐藤信一郎, 宇尾基弘, 亘理文夫, 林大輔, 高田知哉
  • Organizer: 第43回フラーレン・ナノチューブ・グラフェン総合討論会
  • Place of Presentation: 東北大学（仙台）
• [Presentation] シクロデキストリン添加によるポルフィリン一次元会合体の形成とその物理化学的特性の検討 (2012)
  • Author(s): 阿部薫明, 小林宏寿, 木場隆之, 亘理文夫, 佐藤信一郎
  • Organizer: 第6回バイオ関連化学
  • Place of Presentation: 北海道大学（札幌）
• [Presentation] グラフェン表面とエチレンカーボネートの相互作用と拡散挙動 (2012)
  • Author(s): 阿部薫明，亘理文夫，田地川浩人
  • Organizer: 第6回分子科学討論会
  • Place of Presentation: 東京大学（東京）
• [Presentation] イオン液体を用いたSEMの新規観察法の開発 (2012)
  • Author(s): 阿部薫明, 兵野篤, 赤坂司, 亘理文夫, 米澤徹
  • Organizer: 第60回日本歯科理工学会学術講演会
  • Place of Presentation: 九州大学（福岡）
• [Presentation] Biocompatibility and biodistribution of several nano-sized ceramics particles (2012)
  • Author(s): S. Abe, Y. Hamba, N. Iwadera, T. Akasaka, S. Yamagata, Y. Yawaka, J. Iida, M. Uo, T. Yonezawa, F. Watari
  • Organizer: 24th International Symposium on Ceramics in Medicine
  • Place of Presentation: Kyushu Universuty (Fukuoka)
• [Presentation] Photophysical properties of europium doped ceramics nanoparticles in bio/medical polymer matrix (2012)
  • Author(s): S. Abe, Y. Hamba, S. Yamagata, M. Uo, J. Iida, T. Kiba, A. Murayama, F. Watari
  • Organizer: MNC2012
  • Place of Presentation: Kobe Meriken Park Oriental Hotel (Kobe)
• [Presentation] イオン液体を用いた生体試料・ナノマテリアルのＳＥＭ観察 (2012)
  • Author(s): 阿部薫明, 兵野篤, 亘理文夫, 米澤徹
  • Organizer: 日本顕微鏡学会第58回シンポジウム
  • Place of Presentation: 北海道大学（札幌）
• [Presentation] SEM observation of nano structured materials using Room Temperature Ionic Liquids (2012)
  • Author(s): S. Abe, F. Watari, A. Hyono, T. Yonezawa
  • Organizer: ICNME2012
  • Place of Presentation: Awaji Yumebutai International Conference Center (Awaji)
• [Presentation] ＳＥＭ観察における生体試料可視化のためのイオン液体の利用
  • Author(s): 阿部薫明、兵野篤、河合功治、亘理文夫、米澤徹
  • Organizer: 日本顕微鏡学会学術講演会
  • Place of Presentation: ホテル阪急エキスポパーク（吹田市）
• [Presentation] イオン液体を用いたナノ/バイオマテリアルのSEM観察
  • Author(s): 阿部薫明、兵野篤、河合功治、米澤徹
  • Organizer: 医学生物学顕微鏡技術学会
  • Place of Presentation: 神奈川歯科大学（横須賀市）
• [Presentation] Scanning Electron Microscope observation of nano/ biological materials with Room Temperature Ionic Liquids
  • Author(s): Shigeaki ABE, Atsushi Hyono, KOji Kawai, and Tetsu Yonezawa
  • Organizer: International Conferene on Solution Chemistry
  • Place of Presentation: Kyoto Terrsa (Kyoto, Japan)
• [Presentation] Biocompatibility and their biodistribution of several nano-sized metal / metal oxide particles
  • Author(s): Shigeaki ABE, Atsushi HYONO, Yuusaku HAMBA, Nobuki IWADERA, Shuuichi YAMAGATA, Fumio WATARI, Tsukasa AKASAKAk, Yasutaka YAWAKA, J.-i. IIDA and Tetsu YONEZAWA
  • Organizer: International Symposium on Surface and Interface Biomaterials
  • Place of Presentation: Roma University (Roma, ITALY)
• [Presentation] Biocompatibility and biodistribution of several micro-/nano-sized inorganic particles
  • Author(s): Shigeaki ABE, Atsushi Hyono, Yusaku Hamba, Nobuki Iwadera, Shuuichi Yamagata, Fumio Watari, Tsukasa Akasaka, Yasutaka Yawaka, J.-i. Iida and Tetsu Yonezawa
  • Organizer: NanOEH
  • Place of Presentation: Nagoya Congress Center (Nagoya, JAPAN)
• [Presentation] イオン液体を用いたバイオマテリアルのSEM新規観察法の開発
  • Author(s): 兵野 篤, 阿部 薫明, 赤坂司, 亘理文夫, 米澤 徹
  • Organizer: 代用臓器・再生医学研究会
  • Place of Presentation: 北海道大学（札幌市北区）
• [Remarks] 阿部薫明
  • URL: http://abeshy.web.fc2.com/index.html