The fundamental Study about regeneration of submandibular gland
| Project/Area Number |
24593011
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OKA Shunichi 日本大学, 歯学部, 准教授 (20256879)
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| Co-Investigator(Renkei-kenkyūsha) |
SHIRATSUCHI Hiroshi 日本大学, 歯学部, 専修医 (50710844)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 唾液腺再生 / 顎下腺 / 細胞骨格 / integrin / duct like structure / in virto / in vitro / duct-like structure / スフェロイド培養 / 成長因子 |
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| Outline of Final Research Achievements |
The aim of this study was to asses alterration in the cytoskeleton and localization of integrin during regeneration of the rat submandibular gland. The findings suggested that alpha3- and alpha6beta1-integrin regulate the regeneration and alterration in cytoskeleton effect regeneration of acinar cell from the duct like structure. Additionally, in vitro investigation of the salivary regeneration was available by this study. We can evaluate the roles of many proteins during regeneration of submandibular gland.
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Report
(4 results)
Research Products
(6 results)
