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Studies on Circadian Rhythms of Intraoral pH and Mature of Young Permanent Tooth

Research Project

Project/Area Number 24593109
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionMeikai University

Principal Investigator

WATANABE Shigeru  明海大学, 歯学部, 教授 (60113049)

Co-Investigator(Kenkyū-buntansha) WATANABE Koji  明海大学, 歯学部形態機能成育学講座 口腔小児科学分野, 講師 (30570650)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords唾液pH / 日内変動 / 幼若永久歯 / エナメル質 / μCT / ミネラル / 成熟 / 石灰化 / エナメル質の成熟 / HUV / 唾液 / 埋伏過剰歯 / saliva pH / salivary flow rate / minor salivary gland / oral environment / エナメル質脱灰
Outline of Final Research Achievements

1) The saliva pH monitoring from 9:00 a.m. to 5:00 p.m. showed above pH 5.5 on both UAL (labial surface of upper central incisor ) and UPB ( buccal surface of upper first molar ) . Minimum pH was about 5.5 and maximum pH was about 7.5 on both. UAL showed higher value than UPB from 9:00 a.m. to 0:00 p.m. and UPB showed higher value than UAL from 1:00 p.m. to 5:00 p.m. On the other hand, while sleeping, from 0:00 a.m. to 7:00 a.m., UAL showed higher value than UPB. We presume that UAL is affected by its contact with labial mucosa, in other words, saliva from minor salivary gland while sleeping.
2) Compared two Hounsfield unit values(HUV), measured values of μCT of enamel, of extracted erupted and impacted supernumerary tooth, the impacted tooth tended to show higher value than erupted supernumerary tooth in the same depth.We obtained a result that challenges conventional theory that, after tooth erupts, enamel matures and bone mineral density gets higher.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (20 results)

All 2015 2014 2013 2012

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (16 results) Book (1 results)

  • [Journal Article] Amount of Calcium Elution and Eroded Lesion Depth in Bovine Enamel Derived from Single Short Time Immersion in Carbonated Soft Drink in Vitro.2015

    • Author(s)
      Koji,Watanabe, Toshiko Tanaka, Kenshi Maki, Hideaki Nakashima, Shigeru Watanabe
    • Journal Title

      Open Journal of Stomatology

      Volume: 5 Pages: 80-86

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model.2012

    • Author(s)
      Zhou SL, Zhou J, Watanabe S, Watanabe K, Wen LY, Xuan K.
    • Journal Title

      J of Dentistry

      Volume: 40(3) Issue: 3 Pages: 255-63

    • DOI

      10.1016/j.jdent.2011.12.016

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Longitudinal evaluation of mineral loss at the earliest stage of enamel demineralization using micro-computed tomography,2012

    • Author(s)
      K. Watanabe, T. Nakamura, T.Ogihara, Y. Ochiai and S. Watanabe
    • Journal Title

      Health

      Volume: 4(6) Issue: 06 Pages: 334-340

    • DOI

      10.4236/health.2012.46055

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] The effect of zinc on enamel remineralization2015

    • Author(s)
      Takashi Ogihara, Akihiro Nakamura, Koji Watanabe and Shigeru Watanabe
    • Organizer
      93rd General Session & Exhibition of the IADR
    • Place of Presentation
      Boston
    • Year and Date
      2015-03-12 – 2015-03-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] フッ化物存在かにおける亜鉛濃度の違いがエナメル質石灰化に与える影響2014

    • Author(s)
      荻原孝、中村昭博、渡辺幸嗣、渡部 茂
    • Organizer
      第29回日本小児歯科学会関東地方会
    • Place of Presentation
      大宮
    • Year and Date
      2014-09-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 炭酸飲料水摂取後の適切な歯磨きのタイミング2014

    • Author(s)
      渡辺幸嗣、田中敏子、中村徳三、渡辺泰平、牧憲司、渡部 茂
    • Organizer
      第29回日本小児歯科学会関東地方会
    • Place of Presentation
      大宮
    • Year and Date
      2014-09-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] Depth of erosive lesion due to carbonated soft drink intake. -In vitro study-2014

    • Author(s)
      Koji Watanabe, Toshiko Tanaka, Takashi Ogihara, Shigeru Watanabe
    • Organizer
      The 11th Int. Conference of Asian Academy of Preventive Dentistry
    • Place of Presentation
      Beijing
    • Year and Date
      2014-09-17 – 2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 小児におけるガムそしゃく前後の口腔細菌数の変化2014

    • Author(s)
      駒澤大悟、荻原孝、江田康輔、吉原幸四郎、渡部 茂
    • Organizer
      第61回日本小児保健協会学術集会
    • Place of Presentation
      福島
    • Year and Date
      2014-06-20 – 2014-06-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 睡眠中の口腔内唾液pHnoモニタリング2014

    • Author(s)
      渡辺泰平、市川智久、木村明子、中村昭博、沼倉春美、吉原」幸四郎、渡辺幸嗣、村本和代、渡部 茂
    • Organizer
      第52回日本小児歯科学会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] Evaluation on anti-demineralization effects of fluoride releasing coat material2013

    • Author(s)
      Watanabe K, Ogihara T, Sasabe T and Watanabe S
    • Organizer
      The 24th IAPD. Seoul, Korea.
    • Place of Presentation
      韓国、ソウル
    • Related Report
      2013 Research-status Report
  • [Presentation] Effect of Fluoride on Remineralization Using Micro CT2013

    • Author(s)
      Ogihara T, Watanabe K and Watanabe S
    • Organizer
      2nd Meeting of the I A D R Asia Pacific Region. Bangkok, Thailand.
    • Place of Presentation
      タイ、バンコク
    • Related Report
      2013 Research-status Report
  • [Presentation] マイクロCTによるエナメル質表層脱灰のミネラル密度の評価2013

    • Author(s)
      落合慶行,荻原 孝,渡辺幸嗣,渡部 茂
    • Organizer
      第51回日本小児歯科学会大会
    • Place of Presentation
      岐阜
    • Related Report
      2013 Research-status Report
  • [Presentation] エナメル質再石灰化に関する基礎的研究―マイクロCTによるエナメル質ミネラル密度の評価―2013

    • Author(s)
      荻原 孝,渡辺幸嗣,渡部 茂
    • Organizer
      第51回日本小児歯科学会大会
    • Place of Presentation
      岐阜
    • Related Report
      2013 Research-status Report
  • [Presentation] 就寝前フッ素洗口によるフッ素の口腔内停滞について2013

    • Author(s)
      白正華、渡部茂、渡辺幸嗣、小口寛子、鈴木亮、雀部貴志
    • Organizer
      第33回日本歯科薬物療法学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] Mineral Transfer between Enamel and Artificial Saliva.2012

    • Author(s)
      S.WATANABE, T.OGIHARA, K.WATANABE, H.KURIHARA, and X.WANG
    • Organizer
      90th General Session & Exhibition of the IADR
    • Place of Presentation
      Iguacu Falls Brazil
    • Related Report
      2012 Research-status Report
  • [Presentation] Longitudinal and pH-dependent evaluation of enamel demineralization using micro-CT2012

    • Author(s)
      Koji Watanabe, Takashi Ogihara, Yoshiyuki Ochiai, Shigeru Watanabe
    • Organizer
      90th General Session & Exhibition of the IADR
    • Place of Presentation
      Iguacu Falls Brazil
    • Related Report
      2012 Research-status Report
  • [Presentation] Evaluation of Successive Changes of Enamel Remineralization by Micro CT2012

    • Author(s)
      Takashi Ogihara, Koji Watanabe, Shoji Takahashi, Shigeru Watanabe
    • Organizer
      The First China International Workshop of Pediatric Dentistry
    • Place of Presentation
      西安 中国
    • Related Report
      2012 Research-status Report
  • [Presentation] マイクロCTを応用した初期脱灰エナメル質のミネラル密度評価-可能性と課題-2012

    • Author(s)
      渡辺幸嗣、荻原孝、落合慶行、渡部茂
    • Organizer
      第50回日本小児歯科学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] エナメル質‐人工唾液間のミネラル移動-マイクロCTによるエナメル質ミネラル密度の評価-2012

    • Author(s)
      荻原孝、渡辺幸嗣、栗原仁、大橋英夫、渡部茂
    • Organizer
      第50回日本小児歯科学会大会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Book] Estimation of the velocity of the salivary film at the different regions in the mouth –Measurement of potassium chloride ij the agar using atomic absorption spectrophotometry- (In) MACRO TO NANO SPECTROSCOPY2012

    • Author(s)
      Shigeru Watanabe.,  (Editor), Jamal Uddin
    • Publisher
      INTECH
    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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