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The effect of reciprocal fixation to keep muscle strength secondary to joint immobilization

Research Project

Project/Area Number 24650327
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionPrefectural University of Hiroshima

Principal Investigator

OKI Sadaaki  県立広島大学, 保健福祉学部, 教授 (10194466)

Project Period (FY) 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywordsリハビリテーション医学 / 廃用性筋萎縮 / 骨格筋 / 萎縮 / 張力 / ラット
Research Abstract

To investigate the effect of reciprocal fixation to keep muscle strength secondary to joint immobilization, an experimental study was carried out. Twenty-four female Wistar rats were used in this study. The rats were divided into four groups (extension fixation group, flexion fixation group, reciprocal fixation group, and control group), each group containing 6 rats. For the extension fixation group, unilateral ankle cast fixations were carried out in extension position. For the flexion fixation group, unilateral ankle cast fixations were carried out in full flexion position. For the reciprocal fixation group, unilateral ankle cast fixations were carried out in full extension position (8 hours a day) and full flexion position (16 hours a day) reciprocally. For the control group, joint fixations were not carried out. After 4 days, isometric twitch tension, maximum tetanic tension, relative weight ratio, and histological change of soleus and tibialis anterior muscles were examined. Muscle atrophy was prevented in the reciprocal fixation group. The maximum tetanic tension of tibialis anterior muscles in the reciprocal fixation group was not enough to the control group. Further maneuver in addition to the reciprocal fixation is needed to keep muscle strength.

Report

(2 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (1 results)

All Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] 廃用性筋萎縮に対する筋伸張位短縮位交互固定法による筋力の維持-ラットによる実験的研究-

    • Author(s)
      沖貞明、積山和加子、梅井凡子、小野武也、大塚彰
    • Journal Title

      総合リハビリテーション

      Volume: (論文採択決定)

    • NAID

      40019819832

    • Related Report
      2012 Final Research Report
    • Peer Reviewed

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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