| Project/Area Number |
24654194
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Plasma science
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| Research Institution | Osaka University |
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Principal Investigator |
KITANO Katsuhisa 大阪大学, 工学(系)研究科(研究院), 准教授 (20379118)
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| Co-Investigator(Kenkyū-buntansha) |
KANEKO Kazuhiro 国立がん研究センター, 東病院, 科長 (30286786)
ITO Masaaki 国立がん研究センター, 東病院, 医長 (40312144)
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| Co-Investigator(Renkei-kenkyūsha) |
KUWATA Takeshi 国立がん研究センター, 東病院, 医長 (00327321)
KOMAI Yoshinobu 国立がん研究センター, 東病院, 医員 (50527067)
KOUSHI Kenichi 国立がん研究センター, 東病院, レジデント (70626829)
IKAWA Satoshi 大阪府立産業技術総合研究所, 主任研究員 (80393297)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 大気圧低温プラズマ / プラズマ医療 / 止血 / 血液凝固因子 / プラズマ止血 / 大気圧プラズマ / 内視鏡 / がん治療 |
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| Research Abstract |
For blood coagulation by low temperature atmospheric plasma, plasma device for endoscope was developed and its hemostatic mechanism was evaluated. The lethality bleed from femoral vein of mouse was controlled with clarity. The bleed from internal organ with partial ablation was also controlled. By pathology assessment, no damege against body cell was seen. Because the shape of red blood cell was kept in blood clot, it seems that some of blood coagulation factor is triggered and plasma directly activate thrombin activation or fibrinogen degradation.
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