Development of a spatial pattern generator that enables isolated stimulation of retinal photoreceptors

• Project/Area Number: 24657177
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: Applied anthropology
• Research Institution: Kagoshima University
• Principal Investigator: TSUJIMURA Seiichi 鹿児島大学, 理工学研究科, 准教授 (10381154)
• Project Period (FY): 2012-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 生理人類学 / メラノプシン神経節細胞 / 網膜錐体細胞 / 刺激提示装置 / 網膜光受容器 / 概日リズム

Research Abstract

The aim of this project was to develop a multi-primary display system that can generate test stimuli with spatio-temporal modulation. Firstly, we modified the multi-primary stimulation system that we had developed in the previous study. We optimized optical components in the system and installed high power LEDs. We also used a micro-computer to control a projector in the system. After these modifications we have achieved a high temporal resolution as we expected.

Research Products

• [Journal Article] Association between melanopsin gene polymorphism (I394T) and pupillary light reflex is dependent on light wavelength (2013)
  • Author(s): Lee, S. I.. Hida, A. Tsujimura, S. Morita, T. Mishima, K. Higuchi, S.
  • Journal Title: Journal of Physiological Anthropology Volume: 32 Issue: 1 Pages: 32-16
  • DOI: 10.1186/1880-6805-32-16
  • Peer Reviewed
• [Journal Article] Melanopsin Gene Polymorphism I394T Is Associated with Pupillary Light Responses in a Dose-Dependent Manner (2013)
  • Author(s): S. Higuchi, A. Hida, S. Tsujimura, K. Mishima, A. Yasukouchi, SI. Lee, Y. Kinjyo, M. Miyahira
  • Journal Title: PLoS One Volume: 8(3) Issue: 3 Pages: e60310-e60310
  • DOI: 10.1371/journal.pone.0060310
  • Peer Reviewed
• [Journal Article] Rod, cone and ipRGC interactions in color perception," The proceedings of the 12th congress of the international colour association 13 (2013)
  • Author(s): S. Tsujimura, N. Hamazono, Y. Saito K. Okajima
  • Journal Title: Newcastle upon Tyne, UK Volume: Vol.4 Pages: 1621-1624
  • Peer Reviewed
• [Journal Article] Melanopsin-Based Brightness Discrimination in Mice and Humans(*equal contribution) (2012)
  • Author(s): TM. Brown, S. Tsujimura, AE.Allen, J.Wynne, R. Bedford, G. Vickery, A. Vugler and RJ. Lucas
  • Journal Title: Current Biology Volume: 22 Pages: 1134-1141
  • Peer Reviewed
• [Journal Article] Melanopsin-based brightness discrimination in mice and humans (2012)
  • Author(s): T. M. Brown, S. Tsujimura, A. E. Allen1, J. Wynne, R. Bedford, G. Vickery, A. Vugler, R. J. Lucas
  • Journal Title: Current Biology Volume: (in press) Issue: 12 Pages: 1134-1141
  • DOI: 10.1016/j.cub.2012.04.039
  • Peer Reviewed
• [Presentation] メラノプシン神経節細胞の輝度経路への時間周波数依存性 (2014)
  • Author(s): 辻村誠一
  • Organizer: 日本視覚学会2014年冬季大会
  • Place of Presentation: 工学院大学
  • Year and Date: 2014-01-23
• [Presentation] A Linear Summation of L- and M-cone Signals in the Pupillary Pathway (2014)
  • Author(s): S. Tsujimura
  • Organizer: Workshop on vision testing in seafarers
  • Place of Presentation: Kobe Port Tower Hotel, Japan
  • Year and Date: 2014-01-21
• [Presentation] A Linear Summation of L- and M-cone Signals in the Pupillary Pathway (2014)
  • Author(s): S. Tsujimura
  • Organizer: Workshop on vision testing in seafarers
  • Place of Presentation: Kobe Port Tower Hotel
• [Presentation] メラノプシンとロービジョン : メラノプシン総論 (2013)
  • Author(s): 辻村誠一
  • Organizer: 第49回日本眼光学学会総会、シンポジウム3
  • Place of Presentation: ウェスティン都ホテル京都
  • Year and Date: 2013-09-08
• [Presentation] 明るさ知覚におけるメラノプシン神経節細胞の寄与 (2013)
  • Author(s): 辻村誠一,岡嶋克典
  • Organizer: 照明学会全国大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2013-09-05
• [Presentation] Cone and melanopsin interaction as a function of temporal frequency (2013)
  • Author(s): S. Tsujimura, N. Hamazono, K. Okajima
  • Organizer: 20th Symposium of the International Colour Vision Society
  • Place of Presentation: Winchester UK
  • Year and Date: 2013-07-16
• [Presentation] メラノプシン神経節細胞の輝度経路への時間周波数依存性 (2013)
  • Author(s): 辻村誠一,濱園直志,岡嶋克典
  • Organizer: 日本生理人類学会
  • Place of Presentation: 金沢
  • Year and Date: 2013-06-09
• [Presentation] メラノプシン遺伝子多型(I394T)と瞳孔の対光反応の関係-光の強度と色光の影響 (2013)
  • Author(s): 李相逸,樋口重和,西剛史,肥田昌子,三島和夫,辻村誠一,森田健,稲見香
  • Organizer: 日本生理人類学会
  • Place of Presentation: 金沢
  • Year and Date: 2013-06-09
• [Presentation] メラノプシン神経節細胞起因信号の時間周波数特性 (2013)
  • Author(s): 再東勇亮,辻村誠一
  • Organizer: 日本視覚学会2013年冬季大会
  • Place of Presentation: 工学院大学
  • Year and Date: 2013-01-25
• [Presentation] メラノプシン神経節細胞と色メカニズムの機能的関連性 (2013)
  • Author(s): 濱園直志,辻村誠一
  • Organizer: 日本視覚学会2013年冬季大会
  • Place of Presentation: 工学院大学
  • Year and Date: 2013-01-25
• [Presentation] Rod, cone and ipRGC interactions in color perception (2013)
  • Author(s): S. Tsujimura, N. Hamazono, Y. Saito K. Okajima
  • Organizer: The international colour association 2013
  • Place of Presentation: Newcastle UK
• [Presentation] メラノプシンとロービジョン：メラノプシン総論 (2013)
  • Author(s): 辻村誠一
  • Organizer: 第４９回日本眼光学学会総会
  • Place of Presentation: ウェスティン都ホテル京都
  • Invited
• [Presentation] 光と睡眠―メラノプシンの発見から最近の照明技術の動向まで : メラノプシン神経節細胞の機能 (2012)
  • Author(s): 辻村誠一
  • Organizer: 日本睡眠学会第37回定期学術集会 : シンポジウムS28-4
  • Place of Presentation: パシフィコ横浜.横浜
  • Year and Date: 2012-06-29
• [Presentation] The contribution of the rod/melanopsin driven ganglion cells to the dynamic pupil light reflex response (2012)
  • Author(s): W. Bi, S. Tsujimura, G. T. Plant, J. L. Barbur
  • Organizer: European Association for Vision and Eye Research
  • Place of Presentation: Nice, France
• [Presentation] Rod and Cone pathways converging on the central targets of melanopsin ganglion cells (2012)
  • Author(s): T. M. Brown, A. E. Allen, S. Tsujimura, R. J. Lucas
  • Organizer: Society for neuroscience
  • Place of Presentation: Washington,DC, USA
• [Presentation] 光と睡眠―メラノプシンの発見から最近の照明技術の動向まで:メラノプシン神経節細胞の機能 (2012)
  • Author(s): 辻村 誠一
  • Organizer: 日本睡眠学会 第37回定期学術集会：シンポジウムS28-4
  • Place of Presentation: 横浜
  • Invited
• [Remarks]
  • URL: http://www.ibe.kagoshima-u.ac.jp/~t_lab/index.html