| Project/Area Number |
24658237
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied animal science
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|---|
| Research Institution | Yamaguchi University |
|---|
Principal Investigator |
KANOH Kiyoshi 山口大学, 共同獣医学部, 准教授 (40312516)
|
|---|
| Project Period (FY) |
2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
|
|---|
| Keywords | 発生工学 / 4倍体 / ES細胞 / マウス |
|---|
| Research Abstract |
Tetraploid mouse embryos is commonly used as tetraploid rescue method in gene targeting. Tetraploid rescue is a method that was designed to utilizing that tetraploid embryos does not contribute to the fetus, intended to obtain pups derived from ES cells, but studies focused on the developmental capacity of tetraploid embryos have not been reported. We have established mouse tetraploid ES cell in order to analyze the early development of tetraploid embryos.
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