Development of in vitro embryotoxic test for nanomaterials
Project/Area Number |
24659075
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Single-year Grants |
Research Field |
Medical pharmacy
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Research Institution | Osaka University |
Principal Investigator |
YOSHIOKA Yasuo 大阪大学, 薬学研究科(研究院), 准教授 (00392308)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | ナノマテリアル / 生殖発生毒性 / 安全性 / 発生毒性試験法 / 胎仔培養法 |
Research Abstract |
Recently, research into potential safety of nanomatelials is increasing. However, few studies are examined the embryotoxicity of nanomatelials. Therefore, we had investigated the embryotoxicity of nanomatelials, and revealed that some nanomatelials might have a potential to cause pregnancy complications. To assess more detail embryotoxicity of nanomatelials, we tried to accumulate the basic information for the development of embryotoxicity method of nanomatelials in vitro.
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Report
(3 results)
Research Products
(15 results)
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[Presentation] In vitro evaluation of the embryotoxic potency of amorphous nanosilica2012
Author(s)
Ogura T., Yoshioka Y., Yamashita K., Taira M., Aoyama M., Tsunoda S., Kawabata K., Mizuguchi H., Nabeshi H., Yoshikawa T., Tsutsumi Y.
Organizer
The 6^<th> International Conference on Nanotoxicology (Nanotoxicology 2012)
Place of Presentation
Beijing, China
Related Report
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[Presentation] Postnatal effects of prenatal exposure to amorphous nanosilica particles on neonatal cognitive functions2012
Author(s)
Morishita Y., Yoshioka Y., Takao K., Ago Y., Satoh H., Nojiri N., Takuma K., Tsunoda S., Nabeshi H., Yoshikawa T., Matsuda T., Miyakawa T., Tsutsumi Y.
Organizer
SETAC Asia/Pacific 2012
Place of Presentation
Kumamoto, Japan
Related Report
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