Research Project
Grant-in-Aid for Challenging Exploratory Research
We developed the effective culture system of human CD8 T cells and effective collection methods of CD8 T cell generating exosomes. We also invented the accurate measurement system of T cell exosomes using the surface molecules of CD8 T cells. We also developed the cancer cell targeting exosomes. We investigated the tumor suppressive effects of cancer cell targeting exosomes in mice with human lung cancer cells or sarcoma cells. We observed how the miRNA including exosomes suppress the luciferase expression in luciferase expressing mice. We also investigated the methods that only hepatic cells can intake exosomes using HBV derived surface molecules.
All 2012
All Book (1 results)
