Research Project
Grant-in-Aid for Challenging Exploratory Research
We changed study design because several genes showed no mutation included in original study design. Thus we analyzed 3' untranslated region (3'UTR) of mRNA that was revealed to be shorten in cancers. 3'UTR is important in post transcriptional regulation of genes and it is known as a target of microRNAs. We firstly analyzed lung cancer specifically shorten mRNA using computational analyses of opened microarray data. We choose ten genes which are shortened in lung cancer and evaluated their status in clinical specimens using with quantitative RT-PCR. We revealed that increase of gene number of 3'UTR shortening is strongly associated post surgical recurrence in lung cancer.
All 2014 2013 2012 Other
All Journal Article (27 results) (of which Peer Reviewed: 15 results) Presentation (10 results) Remarks (1 results)
Annals of Thoracic and Cardiovascular Surgery
Volume: 20 Issue: Supplement Pages: 582-584
10.5761/atcs.cr.12.02217
130003377861
J Thorac Car diovasc Surg
Volume: 145(2) Pages: 522-530
Cancer Chemother Pharmacol
Volume: 71(1) Pages: 85-92
Amer ican J of Sur g. Pathology
Volume: 37(6) Pages: 924-932
Int J Clin Exp Pathol
Volume: 6(4) Pages: 598-612
Anticancer Res
Volume: 33(6) Pages: 2619-2622
Ann Thorac Cardiovasc Sur g
Volume: (Epub ahead)
Cancer Sci
Volume: 104(11) Pages: 1447-1454
Case Rep Med
Pages: 354507-354507
Frontier s in Genetics
Volume: 4 Pages: 275-275
Frontiers in Genetics
Case Reports in Medicine
Volume: 2013 Pages: 354507-354507
10.1155/2013/354507
Volume: 104 Issue: 11 Pages: 1447-1454
10.1111/cas.12250
Anticancer Research
Volume: 33 Pages: 2619-2622
Am J Surg Pathol
Volume: 37(6) Issue: 6 Pages: 924-932
10.1097/pas.0b013e31827e1e83
International Journal of Clinical & Experimental Pathology
Volume: 6 Pages: 598-612
Volume: Epub ahead
The Journal of Thoracic and Cardiovascular Surgery
Volume: 145 Issue: 2 Pages: 522-530
10.1016/j.jtcvs.2012.03.010
Cancer Chemotherapy and Pharmacology
Volume: 71 Issue: 1 Pages: 85-92
10.1007/s00280-012-1981-0
American Journal of Surgical Pathology
Volume: in press
International Journal of Clinical and Experimental Pathology
Int J Cancer
Volume: 130(11) Pages: 2580-2590
J Thorac Imaging
Volume: 27(4)
J pn J Clin Oncol
Volume: 42(2) Pages: 148-152
Int J Cancer.
Volume: 130 Issue: 11 Pages: 2580-2590
10.1002/ijc.26254
Volume: 27 Issue: 4 Pages: W97-W99
10.1097/rti.0b013e3182282d17
Jpnease Journal of Clinical Oncology
Volume: 42 Issue: 2 Pages: 148-152
10.1093/jjco/hyr179
http://kokyuki.umin.jp/305.html