| Project/Area Number |
24659366
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Gastroenterology
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| Research Institution | Kobe University |
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Principal Investigator |
AZUMA Takeshi 神戸大学, 医学(系)研究科(研究院), 教授 (60221040)
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| Co-Investigator(Kenkyū-buntansha) |
TOYONAGA Takashi 神戸大学, 医学部附属病院, 准教授 (40464268)
MORITA Yoshinori 神戸大学, 医学部附属病院, 講師 (60420460)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 消化器内視鏡 / レーザー / 内視鏡治療 / 炭酸ガスレーザー / 内視鏡治療機器 / 内視鏡的粘膜下層剥離術 / 内視鏡的粘膜剥離術 |
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| Research Abstract |
We developed CO2 laser system with flexible thin hollow optical fibers transmitting mid-infrared light. The energy of the CO2 laser was absorbed by the water and did not reach the muscularis propria of GI tract. In the ex vivo and in vivo study using pigs, en bloc resections were achieved without perforation and muscular damage. Endoscopic submucosal dissection using a CO2 laser with a submucosally injected laser absorbent might be a feasible method for the treatment of early GI tract cancer.
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