| Project/Area Number |
24659502
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pediatrics
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
SUTO Fumiaki 京都府立医科大学, 医学(系)研究科(研究院), 研究員 (20271166)
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| Co-Investigator(Kenkyū-buntansha) |
HIDAKA Kyouko 北九州市立大学, 教授 (00216681)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 分化型刺激伝導系細胞 / 多能性幹細胞 / HCN4チェンネル / 細胞外エピトープ / ＨＣＮ４チャンネル / 心筋細胞 / 刺激伝導系心筋細胞 / 刺激伝導系細胞 / HCN4 channel |
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| Outline of Final Research Achievements |
Many investigators have been trying to develop primitive not well differentiated cardiomyoctes such as pacemaker cells from pluripotent stem cell.In this project we were aiming to isolate pacemaker cells from mixed cardiomyocytes by cell sorter technique, using antibodies targeting extracelluar sequence, 288-293, 362-368, 442-447, and 487-496 of HCN4 channel. However, we could not sort effective pacemaker cells using these HCN4 antibodies.
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