| Project/Area Number |
24659761
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Tottori University |
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Principal Investigator |
KANEDA SHUZO 鳥取大学, 医学部, 助教 (20548747)
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| Co-Investigator(Kenkyū-buntansha) |
MIYAZAKI Dai 鳥取大学, 医学部附属病院, 講師 (30346358)
INOUE Yoshitugu 鳥取大学, 医学部, 教授 (10213183)
IKEDA Yoshifumi 鳥取大学, 医学部, 助教 (10444639)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 血管移植併用緑内障手術 / 1緑内障手術 / 緑内障手術 |
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| Outline of Final Research Achievements |
Establishment of surgical technique of a new intraocular pressure control for refractory glaucoma, the research for the purpose of implant development for biocompatible highly drainage of aqueous fluid which is capable of reducing the frequency of complications were conducted. The auricular artery of Japanese white rabbits was subjected to glaucoma filtration surgery performed by autologous transplantation. The result, significant intraocular pressure lowering or more postoperative 6 months was obtained. Problems such as the anterior chamber fixing method of graft vessel remained. Result from surgery white rabbits of histological examination of the excised graft vessel, the vessel lumen structure is kept, it is believed that the graft vessel was functioning as a drainage path. The results of this study, we have found the possibility of a new glaucoma surgery procedures using autologous blood vessels.
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