Development of real-time image analysis system of cervical lymph node network using nanobubbles
| Project/Area Number |
24659834
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KODAMA Tetsuya 東北大学, 医工学研究科, 教授 (40271986)
IIKUBO Masahiro 東北大学, 歯学研究科, 講師 (80302157)
KOJIMA Ikuho 東北大学, 歯学研究科, 助教 (80447169)
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| Co-Investigator(Renkei-kenkyūsha) |
MORI Shiro 東北大学, 大学病院, 講師 (80230069)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | ナノバブル / 超音波 / リンパネットワーク / 画像解析 / リンパ節 / リンパ節転移 / 画像診断 / センチネルリンパ節 |
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| Outline of Final Research Achievements |
The aim of this study is to develop a new diagnostic imaging technique which can detect the head and neck cancer metastasis routes. In this study, MXH10 / Mo / lpr mice, which develop systemic swelling of lymph nodes up to 10 mm in diameter, were used as a lymph node metastasis model. As a method for visualization of lymph node network in real time, we examined a contrast ultrasound imaging system using nano-microbubbles. As a result, it was suggested that contrast ultrasound image analysis method using a nano-micro-bubbles might be a potential method clinically applicable to detection of lymphatic network.
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Report
(4 results)
Research Products
(53 results)
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[Journal Article] Imaging of transplanted islets by positron emission tomography, magnetic resonance imaging, and ultrasonography2013
Author(s)
Sakata N, Yoshimatsu G, Tsuchiya H, Aoki T, Mizuma M, Motoi F, Katayose Y, Kodama T, Egawa S, Unno M.
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Journal Title
Islets
Volume: 14
Pages: 179-187
Related Report
Peer Reviewed
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