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Cohort Study on the Relation between Infection of Periodontopahic Bacteria and Safety of Dental Implants

Research Project

Project/Area Number 24659924
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Periodontal dentistry
Research InstitutionOkayama University

Principal Investigator

TAKASHIBA Shogo  岡山大学, 医歯(薬)学総合研究科, 教授 (50226768)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords歯周病 / 歯周病原細菌 / 口腔インプラント
Research Abstract

Oral rehabilitation with oral implant has been widely performed with less consideration for infection of oral bacteria. Thus, it is reasonable to assume that latent oral infection such as periodontitis affects the prognosis of oral rehabilitation with oral implant.
This research project drew up a clinical research plan in order to clarify this clinical question. Both a research plan named as "An evaluation of oral bacterial infection before and after oral rehabilitation with oral implant using plasma IgG titer test against periodontopathic bacteria" and a comprehensive evaluation method for the change of oral microflora were proposed.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (12 results)

All 2014 2013 2012 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (10 results)

  • [Journal Article] Effect of Porphyromonas gingivalis outer membrane vesicles on gingipain-mediated detachment of cultured oral epithelial cells and immune responses2014

    • Author(s)
      Nakao R, Takashiba S, Kosono S, Yoshida M, Watanabe H, Ohnishi M, Senpuku H.
    • Journal Title

      Microbes and Infection

      Volume: 16 Issue: 1 Pages: 6-16

    • DOI

      10.1016/j.micinf.2013.10.005

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT2013

    • Author(s)
      Hirai K, Maeda H, Omori K, Yamamoto T, Kokeguchi S, Takashiba S
    • Journal Title

      Pathogens and Disease

      Volume: 68(1) Issue: 1 Pages: 12-19

    • DOI

      10.1111/2049-632x.12041

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Presentation] DNA normalizationを応用した高感度な細菌叢解析法の検討2013

    • Author(s)
      松永一幸,工藤値英子,河田有祐,前田博史,高柴正悟
    • Organizer
      第34回岡山歯学会総会・学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2013-10-27
    • Related Report
      2013 Final Research Report
  • [Presentation] DNA normalizationを用いた細菌叢解析法確立のためのPilot study2013

    • Author(s)
      松永一幸,工藤値英子,河田有祐,前田博史,高柴正悟
    • Organizer
      第6回日本口腔検査学会総会・学術大会
    • Place of Presentation
      鶴見
    • Year and Date
      2013-09-15
    • Related Report
      2013 Final Research Report
  • [Presentation] T-RFLP法による高感度な細菌叢解析法確立のためのPilot Study2013

    • Author(s)
      松永一幸,工藤値英子,河田有祐,前田博史,高柴正悟
    • Organizer
      日本歯科保存学会2013年度春季学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2013-06-27
    • Related Report
      2013 Final Research Report
  • [Presentation] Methanobrevibactor oralisおよびヒトのグループIIシャペロニンに対する免疫応答の解析2013

    • Author(s)
      平井公人,前田博史,山城圭介,大森一弘,峯柴淳二,山本直史,苔口進,高柴正悟
    • Organizer
      第56回春季日本歯周病学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2013-05-31
    • Related Report
      2013 Final Research Report
  • [Presentation] 歯周病原細菌感染度を指標に用いた口腔インプラント施術前後の10年間の追跡調査研究の提案2012

    • Author(s)
      工藤値英子,峯柴淳二,畑中加珠,高木慎,飯田征二,前田博史,高柴正悟
    • Organizer
      第33回岡山歯学会総会・学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2012-11-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 歯周病原細菌感染度を指標に用いた口腔インプラント施術前後10年間の追跡調査研究の提案2012

    • Author(s)
      工藤値英子,畑中加珠,前田博史,高柴正悟
    • Organizer
      第55回日本歯周病学会秋季学術大会
    • Place of Presentation
      つくば市
    • Year and Date
      2012-09-22
    • Related Report
      2013 Final Research Report
  • [Presentation] インプラント周囲炎予防のための細菌学的検査による評価基準設定を視野に入れた長期コホート研究の提案2012

    • Author(s)
      工藤値英子,畑中加珠,前田博史,高柴正悟
    • Organizer
      第5回日本口腔検査学会総会・学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-08-25
    • Related Report
      2013 Final Research Report
  • [Presentation] DNA normalizationを応用した高感度な細菌叢解析法の検討

    • Author(s)
      松永 一幸, 工藤 値英子, 河田 有祐, 前田 博史, 高柴 正悟
    • Organizer
      第34回 岡山歯学会総会・学術集会
    • Place of Presentation
      岡山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 歯周病原細菌感染度を指標に用いた口腔インプラント施術前後10年間の追跡調査研究の提案

    • Author(s)
      工藤値英子,峯柴淳二,畑中加珠,高木慎,飯田 征二,前田博史,高柴正悟
    • Organizer
      第33回 岡山歯学会総会・学術集会
    • Place of Presentation
      岡山市
    • Related Report
      2012 Research-status Report
  • [Presentation] 歯周病原細菌感染度を指標に用いた口腔インプラント施術前後10年間の追跡調査研究の提案

    • Author(s)
      工藤値英子,畑中加珠,前田博史,高柴正悟
    • Organizer
      第55回 日本歯周病学会 秋季学術大会
    • Place of Presentation
      つくば市
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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