| Budget Amount *help |
¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000)
Fiscal Year 2014: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2012: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
|
|---|
| Outline of Final Research Achievements |
Recently, the numbers of human and animal patients with chronic kidney disease (CKD) have been increasing. It is crucial to diagnose and start treatment as an early therapeutic strategy for CKD. In this study, several animals were analyzed in order to use microRNAs as an early diagnostic tool for CKD. Specific microRNAs that indicated the progression of CKD were detected in the urine. These microRNAs were expressed in the kidneys of mice, as well as in those of dogs, cats, and humans, and could be used as an early diagnostic tool (biomarkers) for CKD.
|
