Development of self-luminescent inorganic nanosheet/enzyme complex for bioimaging
| Project/Area Number |
24750072
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Analytical chemistry
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| Research Institution | Saga University |
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Principal Investigator |
SOH Nobuaki 佐賀大学, 農学部, 准教授 (90336008)
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| Research Collaborator |
KAMADA Kai 長崎大学, 大学院工学研究科, 准教授 (90315284)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 無機ナノシート / 酵素 / 発光 / 蛍光 / バイオ材料 |
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| Outline of Final Research Achievements |
Novel hybrid materials ((i) a hybrid material composed of fluorescent inorganic nanosheet and enzyme (ii) a hybrid material composed of fluorescent compound, non-fluorescent inorganic nanosheet, and enzyme) were developed for imaging application. Europium-doped layered titanates show fluorescent properties and the fluorescence intensity increased with an increase in the concentration of doped europium. Fluorescence derived from chemiluminescent resonance energy transfer (CRET) was observed when luminol derivative was applied to a hybrid material composed of fluorescent beads, horseradish peroxidase (HRP), layered titanates.
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Report
(4 results)
Research Products
(17 results)
