Development of sarcomere-like microactuators driven by motor proteins
Project/Area Number |
24760203
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Intelligent mechanics/Mechanical systems
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Research Institution | Gifu University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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Keywords | モーター蛋白質 / 細胞骨格 / 微細加工 / マイクロアクチュエータ / シミュレーション / キネシン / 微小管 / アクチュエータ |
Outline of Final Research Achievements |
Motor proteins, such as kinesin and myosin, are biological molecular machines working in cells, and have been integrated into MEMS and lab-on-a-chips as their driving forces. Here, we aimed at developing a microactuator with motor proteins and cytoskeletal filaments anchored onto microfabricated scaffolds. To this end, we fabricated microscopic cylindrical particles serving as the scaffolds, and bound them with motor proteins and cytoskeletons. In addition, we developed a computer simulation which aids the development of the microactuator.
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Report
(4 results)
Research Products
(13 results)