| Project/Area Number |
24780259
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Azabu University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 肝障害 / 周産期 / 乳牛 / 肝機能 / IGF-1 |
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| Research Abstract |
A liver damage is easy to be caused by a defect of nutritional management in peripartum period of the dairy cow, and the reduced secretion of IGF-1 which is a regulatory factor of the follicle growth causes a breeding disorder. By administration of the Rhizopus oryzae water extract that an inhibitory effect of liver damage was recognized in a liver injury model rat to a dairy cow of the latter stage of non-lactating period, analysis was performed for the purpose of proving that reproductive performance improved by controlling a potential liver damage and improving the IGF-1 secretion of the liver. As a result, the suppression of the liver damage by the water extract was found to be important to improvement of the reproductive performance such as shortening of the days until return of estrus and improvement of conception rate through recovery of the IGF-1 secretion ability and energy balance improvement.
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