Project/Area Number |
24790033
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Chemical pharmacy
|
Research Institution | Kyushu University of Health and Welfare |
Principal Investigator |
OHTSUKA Isao 九州保健福祉大学, 薬学部, 准教授 (20389589)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | 糖鎖合成 / 有機化学 / ケミカルバイオロジー / シアリルルイスX / 糖鎖-レクチン認識 / 光アフィニティーラベル法 / 光反応基 |
Research Abstract |
2 kinds of trisaccharide ligands were synthsized, Sia-Gal-GlcNAc and Gal-(Fuc)-GlcNAc. But tetra saccharide ligand, Sia-Gal-(Fuc)-GlcNAc, was not synthesized.Synthesis of branch part of oligosaccharide were very difficult.Synthesis of thier compounds will affect toward to the elucidation of carbohydrate and lectin interactions.
|