The brain mechanism of obesity-induced anxiety and depression: a role of PrRP-synthesizing neurons.
Project/Area Number |
24790237
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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Research Institution | Jichi Medical University |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2014-03-31
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | ストレス / プロラクチン放出ペプチド / PrRP |
Research Abstract |
Emotional stress activated prolactin releasing peptide (PrRP)-synthesizing neurons. The medial amygdala-medullary PrRP-synthesizing neuron pathway was suggested to have an important role for neuroendocrine responses to emotional stress. Food intake activates PrRP-synthesizing neurons and endogenous PrRP has anorexic action. Cholecystokinin-PrRP-oxytocin pathway was suggested to play an important role in the control of the termination of each meal.
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Report
(3 results)
Research Products
(12 results)
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[Journal Article] Involvement of prolactin-releasing peptide in the activation of oxytocin neurones in response to food intake.2013
Author(s)
Yamashita,M., Takayanagi,Y., Yoshida,M., Nishimori,K., Kusama, M. and Onaka,T.
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Journal Title
Journal of Neuroendocrinology
Volume: 25
Issue: 5
Pages: 455-465
DOI
Related Report
Peer Reviewed
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