| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
We compared the grafting efficiency of undifferentiated cell, early mesodermal cells, cardiomyocytes (early- and middle-stage) from human iPS cells in transplantation into mouse hearts, and found that middle-stage differentiated cardiomyocytes can be grafted efficiently. We also observed that transplanted differentiated cardiomyocytes can survive and maturate in the infarcted mouse hearts and improve the cardiac function.
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