| Project/Area Number |
24790789
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Circulatory organs internal medicine
|
|---|
| Research Institution | Fukuoka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | HDL機能 / コレステロール引き抜き能 / 抗酸化能 / ステント内再狭窄 / 禁煙 / 高比重リポ蛋白(HDL) / HDL機能解析 |
|---|
| Research Abstract |
The major findings of our study are that the cholesterol efflux capacity but not anti-oxidative capacity of HDL was significantly associated with in-stent late loss after stent implantation, and that compared with patients with the higher efflux capacity, patients with the lower efflux capacity demonstrated increased risk of higher in-stent late loss.
We also found that smoking cessation leads to the improvement of HDL functionality (cholesterol efflux capacity and anti-oxidative capacity) without changing HDL-C, apoA-I levels and HDL subfractions.
|
