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Research on mechanism of neonatal hypoxic-ischemic encephalopathy using microscopic mass-spectroscopy

Research Project

Project/Area Number 24791121
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Embryonic/Neonatal medicine
Research InstitutionKeio University

Principal Investigator

TAKENOUCHI Toshiki  慶應義塾大学, 医学部, 助教 (60383741)

Research Collaborator SUEMATSU Makoto  慶應義塾大学, 医学部, 教授
KAJIMURA Mayumi  慶應義塾大学, 医学部, 准教授
NAKANISHI Tsuyoshi  慶應義塾大学, 医学部, 特別研究講師
SUGIURA Yuki  慶應義塾大学, 医学部, 特別研究講師
NAGAHATA Yoshiko  慶應義塾大学, 医学部, 研究補助員
SUGIOKA Tadao  慶應義塾大学, 医学部, 共同研究員
MATSUURA Tomomi  慶應義塾大学, 医学部, 研究補助員
HISHIKI Takako  慶應義塾大学, 医学部, 特別研究講師
MORIKAWA Takayuki  慶應義塾大学, 医学部, 特別研究助教
KUBO Akiko  慶應義塾大学, 医学部, 特別研究講師
TAKAHASHI Takao  慶應義塾大学, 医学部, 教授
Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords新生児 / 低酸素虚血 / 脳障害 / 低体温療法
Research Abstract

The present study was undertaken to reveal mechanisms of hypothermic intervention in neonatal hypoxic-ischemic encephalopathy. Using animal models, we have demonstrated detailed intracerebral metabolic changes, which would contribute to improvement in the hypothermic treatment strategy.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2013 Other

All Presentation (3 results)

  • [Presentation] Metabolic responses to therapeutic hypothermia after hypoxia-ischemia in newborn rats2013

    • Author(s)
      武内俊樹
    • Organizer
      Society for Neuroscience 2013
    • Place of Presentation
      アメリカ合衆国カリフォルニア州サンディエゴ市
    • Year and Date
      2013-11-10
    • Related Report
      2013 Final Research Report
  • [Presentation] Metabolic responses to mild hypothermia treatments after hypoxia-ischemia in newborn rats2013

    • Author(s)
      武内俊樹
    • Organizer
      第38回日本微小循環学会総会
    • Place of Presentation
      東京慈恵会医科大学(東京都港区西新橋)
    • Related Report
      2012 Research-status Report
  • [Presentation] Metabolic responses to therapeutic hypothermia after hypoxia-ischemia in newborn rats

    • Author(s)
      武内俊樹、中西豪、杉浦悠毅、長畑善子、杉岡忠男、久保亜希子、高橋孝雄、梶村眞弓、末松誠
    • Organizer
      Society for Neuroscience 2013
    • Place of Presentation
      San Diego, CA, USA
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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