| Project/Area Number |
24791339
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | MRI / 脳梗塞 / DKI / 脳梗塞拡散画像 / QSI/DKI |
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| Research Abstract |
Subjects were 27 stroke patients presenting with cerebral white matter, cortex, cerebellum, brainstem or basal ganglia infarction (time after onset= 3hours~29days). All subjects were scanned Diffusional kurtosis imaging (DKI) that is more advanced diffusional imaging and diffusion tensor imaging (DTI) that is conventional diffusional imaging on 1.5T MR scanner. Regions of interest were defined for each stroke lesion. Parameter of DKI: mean diffusional kurtosis (MDK) and DTI parameters were calculated. In result, it indicates that MDK add pathological information differing from DTI. In short, the value of MDK indicates complexity of the tissue. It helps us to understand pathological change of stroke lesion. And MDK map can predict the outcome of stroke lesion 1 month earlier than conventional diffusional imaging.
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