| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
In clinical study, characterization of clinical isolates of Escherichia coli (E. coli) isolated from urinary tract infection; development of culture medium in which drug-resistant E. coli isolates could be selectively cultured; investigation of administration duration of antimicrobials against uncomplicated cystitis; evaluation of penetration of various antimicrobials to human epididymis tissue, were completely performed.
In basic research, analysis of bacterial gene related with drug resistance; construction of mice model of urinary tract infection; evaluation of administration manner of antimicrobials using the model, were performed. However, effective dose and duration of antimicrobial treatment against biofilms in urinary tract could not be clarified.
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