| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Outline of Final Research Achievements |
Fertilization is essential event for development. However, there is a lot of person who suffer from infertility. And so, I elucidated the factor which concern with fertilization in order to assist for infertility. As a result, citrate synthase-like was found as the new factor in mouse, the mammal model. Citrate synthase-like triggered Ca2+ increase in egg cytoplasm on introducing into the egg, and then was began the development of zygote. Also, enzyme activity in citrate synthase-like or interaction between other molecules and citrate synthase-like seems to be concerned with Ca2+ increase in egg cytoplasm. Furthermore, I am intend to clarify functions and mechanism of citrate synthase-like in fertilization.
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