| Project/Area Number |
24791811
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|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Jikei University School of Medicine |
|---|
Principal Investigator |
ASAKA Daiya 東京慈恵会医科大学, 医学部, 講師 (20317928)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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|---|
| Keywords | サイトカイン / バイオフィルム / クラスター解析 / IL-33 |
|---|
| Research Abstract |
Chronic rhinosinusitis (CRS) is a heterogeneous disease whose pathophysiology is not fully understood. Recently, cluster analysis has been used to classify the phenotypes and subtypes of asthma and food allergy. The aim of this study was to investigate CRS phenotype using cluster analysis. A total of 22 patients were enrolled in this study. The range of peripheral blood eosinophil counts were 0.8-25.3%. Serum total IgE were 25-1432IU/ml. Mucosal tissues eosinophilia were 12-320 eosinophils/HPF. Cluster analysis that added measurement of cytokine did not indicate significant difference. So it is important to accumulation of the number of cases of patients in future.
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