Enhancement of functional expression of osteoblastic and periosteal cells by gingival fibroblasts with paracrine effect of fibroblastic growth factors
Project/Area Number |
24792114
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Prosthetic dentistry
|
Research Institution | Tokyo Dental College |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
Keywords | 骨再生 / 線維芽細胞増殖因子 / 歯肉結合組織 / 細胞間相互作用 / 歯肉線維芽細胞 |
Research Abstract |
Gingival fibroblasts enhanced osteoblastic and periosteal proliferation and differentiation. The mechanism was involved in paracrine secretion of FGF-1 and -18 from GF and subsequent autocrine secresion of these growth factors from osteoblasts and periosteal cells.
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Report
(3 results)
Research Products
(40 results)