| Project/Area Number |
24792284
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 歯科矯正学 / 顔面形態 / 歯科矯正 / 不正咬合 / 下顎骨 / エピジェネティクス |
|---|
| Research Abstract |
A rat fed with soft diet changes its cranial and mandibular form compared to a rat fed with hard diet. In this time, we assess the analysing method for the form of mandibular with advancing 3DCT and orthodontics cephalometric analysis. As a result, we could detect refined change of mandibular form in mice between grown with powdery feed and with fixed hard feed.
Additionally, we analysed gene expression in masseter muscles in these two group mice. Some gene expression were significantly changed between these two groups. Further more, I find outthe reaction of MYH genes expression which play a role in deciding a character of muscle.
These finding showes that the hardness of feed may influence to the form of mandibular via the change of chalacter of masseter muscle.
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