| Project/Area Number |
24890031
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | University of Tsukuba |
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Principal Investigator |
KATO Yoshiaki 筑波大学, 医学医療系, 講師 (90635608)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 胎児 / 心磁図 / 心拍変動解析 / 先天性心疾患 / 循環器・高血圧 / 母体自己抗体 / 新生児 / 心電図 |
|---|
| Research Abstract |
Technological advances in fetal magnetocardiography (fMCG) have made it possible to record fetal cardiac electrical activities with high time resolution, and enabled us to apply heart rate variability (HRV) analysis in fetuses. We analyzed 154 records of 154 normal fetuses and 57 records of 37 fetuses with congenital heart diseases (CHD). HRV analysis, including both time domain and frequency domain analysis, was applied. In normal fetuses, the total heart rate variability increased with gestational age, which is suggested to be the result of development of autonomic nervous system. In frequency analysis,the power in wide range was significantly low in one CHD fetus with heart failure. HRV analysis may be helpful in assessment of severity of heart failure in CHD fetuses.
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