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Development of Oral Infection Control System with Natural and Artificial materials

Research Project

Project/Area Number 24890134
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Conservative dentistry
Research InstitutionOkayama University

Principal Investigator

ITO Takashi  岡山大学, 医歯(薬)学総合研究科, 助教 (30636238)

Project Period (FY) 2012-08-31 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords口腔内感染症 / 糖類 / 多糖 / 糖鎖
Research Abstract

The aim of this study was to evaluate interaction of artificial phosphated pullulan and natural lectin as oral infection control systems.Contriving adaptation of these materials improved efficacy by analyzing interaction.The algal lectin used in this study may offer a novel strategy to reduce development of infection on saliva-coated surface by inhibiting the initial adhesion and subsequent biofilm formation of S. mutans.
In future, natural lectin is applied as a food, phosphated pullulan as oral care agent.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • Research Products

    (9 results)

All 2014 2013 2012 Other

All Presentation (8 results) Remarks (1 results)

  • [Presentation] Development of Functional food with Infection Control Effect by Mushroom Extract2014

    • Author(s)
      伊東孝
    • Organizer
      日本歯科保存学会2014年春期学術大会(第140回)
    • Place of Presentation
      滋賀
    • Related Report
      2013 Final Research Report
  • [Presentation] Development of Functional Food with Infection Control Effect by Mushroom Extract2014

    • Author(s)
      伊東 孝
    • Organizer
      日本歯科保存学会2014年度春季学術大会(第140回)
    • Place of Presentation
      滋賀
    • Related Report
      2013 Annual Research Report
  • [Presentation] 海藻由来レクチンによる口腔感染制御能を有した機能性食品の開発2013

    • Author(s)
      塩田康祥
    • Organizer
      第20回日本未病システム
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] Oral Biofilm Inhibition Effect and the Cytotoxicity Test of Codium Fragile Extract2013

    • Author(s)
      塩田康祥
    • Organizer
      10^<th> Asian Pacific Society of Periodontology Meeting
    • Place of Presentation
      奈良
    • Related Report
      2013 Final Research Report
  • [Presentation] 海藻由来レクチンによる口腔感染制御能を有した機能性食品の開発2013

    • Author(s)
      塩田 康祥
    • Organizer
      第20回日本未病システム学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Oral Bofilm Inhibition Effect and The Cytotoxicity Test of Codium Fragile Extract2013

    • Author(s)
      塩田 康祥
    • Organizer
      10th Asian Pacific Society of Periodontology Meeting
    • Place of Presentation
      奈良
    • Related Report
      2013 Annual Research Report
  • [Presentation] Inhibition of oral biofilm formation by Codium fragile extract.2012

    • Author(s)
      塩田 康祥
    • Organizer
      第98回アメリカ歯周病学会共催日本歯周病学会2012年大会
    • Place of Presentation
      Los Angels
    • Related Report
      2012 Annual Research Report
  • [Presentation] Streptococcus mutansのバイオフィルム形成に対するレクチン抑制機構の解析2012

    • Author(s)
      伊東 孝
    • Organizer
      第19回日本未病システム学会
    • Place of Presentation
      金沢
    • Related Report
      2012 Annual Research Report
  • [Remarks] Periodontal Science

    • URL

      http://www.cc.okayama-u.ac.jp/~perio/bind2/index.html

    • Related Report
      2012 Annual Research Report

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Published: 2012-11-27   Modified: 2019-07-29  

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