| Project/Area Number |
24890238
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2012-08-31 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | MPC / 義歯 / デンチャープラーク / 歯学 / MPC polymer / denture base resin / anti-biofilm formation / surface modification |
|---|
| Research Abstract |
MPC polymers have significant biocompatibility, are highly resistant to cell adhesion, and do not react with multiproteins. We have been studying for development of "the anti-adhesive denture" unattached dental plaque by MPC coating to denture surface. Previously, we have tested MPC coating on the dentures by using graft polymerization method, which have superior durability. However, we have found operability problem on this method. So, we examined the new method such as coating of contents mixed 2-HEMA and MPC, and of PMBPAz polymer copolymerized MPC and BMA. At the moment, we have reached clinical study with the PMBMAz polymer coating.
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