| Budget Amount *help |
¥46,280,000 (Direct Cost: ¥35,600,000、Indirect Cost: ¥10,680,000)
Fiscal Year 2016: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
Fiscal Year 2015: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2014: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2013: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
|
|---|
| Outline of Final Research Achievements |
Meiosis is an important biological event that produces genetic diversity of eukaryotes. This project analyzed molecular functions of three rice proteins important for meiosis progression. MEL2 controls meiotic entry in rice. We identified the RNA consensus sequence that MEL2 preferentially bound in vitro, and predicted the genes under the control of MEL2. Next, the analyses of germline-specific Argonaute MEL1 and anther tapetum-specific transcription factor EAT1 revealed possibilities that small RNAs regulated male meiosis non-cell autonomously, and triggered chromosome remodeling in male meiocytes. These findings unveiled that RNA-mediated epigenetic regulatory mechanisms play essential roles in progression of plant meiosis.
|
