Study of hippocampal function with electrical activity in temporal cognition
| Project/Area Number |
25280051
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cognitive science
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| Research Institution | Hiroshima University |
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Principal Investigator |
Sakata Shogo 広島大学, 総合科学研究科, 教授 (50153888)
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| Co-Investigator(Kenkyū-buntansha) |
Ito Isao 九州大学, 理学研究院, 教授 (20183741)
Okada Kana 広島大学, 大学院総合科学研究科, 特任助教 (50528263)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥16,770,000 (Direct Cost: ¥12,900,000、Indirect Cost: ¥3,870,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Keywords | 時間認知 / 脳認知科学 / 時間情報処理 / 海馬機能 / 海馬の非対称性 / 海馬シータ波 / ピーク法 |
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| Outline of Final Research Achievements |
Time is truly ubiquitous. Time is very important to living animals. This study focused on the hippocampal function in the temporal cognition and was going to clarify the relationship between brain region and their electrophysiological activity. Rats were trained using peak interval (PI) 30-s procedure that include empty probe trials using at response peak time and measured the hippocampal θ activity during PI task performance. It can calculate to evaluate as a power level by doing FFT analysis. We have measured as an objective evaluation of the hippocampal θ wave how it works. We sorted progress and the correspondency of the hippocampal θ wave in frequency band at peak time. Even mice were able to attract behavioral data by long-term training using the same PI procedure. There is the electroencephalographic comparison between the iv mouse which reversed the right and left components and C57BL/6J which is generally used by an experiment in the future study.
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Report
(4 results)
Research Products
(27 results)
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[Journal Article] Enhanced flexibility of place discrimination learning by targeting of striatal cholinergic interneurons.2014
Author(s)
Okada, K., Nishizawa, K., Fukabori, R., Kai, N., Shiota, A., Ueda, S., Tsutsui, Y., Sakata, S., Matsushita, N., and Kobayashi, K.
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Journal Title
Nat. Commun.
Volume: 5
Issue: 1
Pages: 3778-3778
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Comprehensive behavioral study of mGluR3 knockout mice: implication in schizophrenia related endophenotypes.2014
Author(s)
Fujioka R, Nii T, Iwaki A, Shibata A, Ito I, Kitaichi K, Nomura M, Hattori S, Takao K, Miyakawa T, Fukumaki Y.
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Journal Title
Mol Brain
Volume: 7
Issue: 1
Pages: 31-31
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Neuronal major histocompatibility complex class I molecules are implicated in the generation of asymmetries in hippocampal circuitry.2013
Author(s)
A. Kawahara, S. Kurauchi, Y. Fukata, J. Hernandez, T. Yagihashi, Y. Itadani, R. Sho, T. Kajiyama, N. Shinzato, K. Narusuye, M. Fukata, R. Lujan, R. Shigemoto, I. Ito.
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Journal Title
Journal of Psysiology
Volume: 591
Pages: 4777-4791
NAID
Related Report
Peer Reviewed
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