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Cortical activities accompanying somatosensory input and transcranial direct current stimulation- MEG and TMS study-

Research Project

Project/Area Number 25282162
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNiigata University of Health and Welfare

Principal Investigator

Onishi Hideaki  新潟医療福祉大学, 医療技術学部, 教授 (90339953)

Co-Investigator(Kenkyū-buntansha) Tamaki Hiroyuki  新潟医療福祉大学, 医療技術学部, 教授 (40253926)
Kirimoto Hikari  新潟医療福祉大学, 医療技術学部, 教授 (40406260)
Sato Daisuke  新潟医療福祉大学, 健康科学部, 准教授 (60544393)
Yamashiro Koya  新潟医療福祉大学, 健康科学部, 講師 (20570782)
菅原 和広  新潟医療福祉大学, 医療技術学部, 助教 (10571664)
鈴木 誠  北里大学, 医療衛生学部, 教授 (80554302)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Keywords脳磁図 / MEG / 他動運動 / 経頭蓋直流電流刺激 / tDCS / 経頭蓋磁気刺激 / 求心性抑制 / 求心性促通 / 運動範囲 / 運動速度 / 体性感覚誘発磁界 / SEF / 機械的触覚刺激 / 短潜時求心性抑制 / TMS / SAI / 運動関連脳磁界 / 運動誘発電位
Outline of Final Research Achievements

We analyzed cortical activities following passive movements (PM), peripheral nerve stimulation and transcranial direct current stimulation to investigate the somatosensory cortical processing following voluntary movement. 1) 3rd component of somatosensory evoked magnetic fields (SEF) following PM reflect cutaneous input. 2) There is no relation between afferent facilitation and the latency of cutaneomuscular reflexes or SEF after digital nerve stimulation. 3) The source strengths for the P35m and the P60m of SEF following median nerve stimulation increased after tDCS was applied over the primary motor cortex (M1) and increased for the P60m after tDCS was applied over the primary somatosensory cortex (S1). 4) Cathodal tDCS over the M1 decreases not only the M1 excitability but also the cortical inhibitory circuits related to short latency afferent inhibition (SAI). In addition, cathodal tDCS applied over the S1 decreased the inhibitory effects of SAI.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (34 results)

All 2016 2015 2014 2013 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results,  Acknowledgement Compliant: 5 results,  Open Access: 4 results) Presentation (22 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results) Book (2 results) Remarks (3 results)

  • [Journal Article] Effect of range and angular velocity of passive movement on somatosensory evoked magnetic fields.2016

    • Author(s)
      Sugawara K, Onishi H, et al.
    • Journal Title

      Brain Topography

      Volume: 13

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Do differences in levels, types, and duration of muscle contraction have an effect on the degree of post-exercise depression?2016

    • Author(s)
      Miyaguchi S, Kojima S, Kirimoto H, Tamaki H, Onishi H
    • Journal Title

      Frontiers in human neuroscience

      Volume: doi Pages: 1-9

    • DOI

      10.3389/fnhum.2016.00159

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Modulation of Cortical Inhibitory Circuits after Cathodal Transcranial Direct Current Stimulation over the Primary Motor Cortex2016

    • Author(s)
      Sasaki R, Miyaguchi S, Kotan S, Kojima S, Kirimoto H, Onishi H
    • Journal Title

      Frontiers in human neuroscience

      Volume: doi Pages: 1-8

    • DOI

      10.3389/fnhum.2016.00030

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Depression of corticomotor excitability after muscle fatigue induced by electrical stimulation and voluntary contraction.2015

    • Author(s)
      Kotan S, Kojima S, Miyaguchi S, Sugawara K, Onishi H
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 9 Pages: 1-7

    • DOI

      10.3389/fnhum.2015.00363

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] No relation between afferent facilitation induced by digital nerve stimulation and the latency of cutaneomuscular reflexes and somatosensory evoked magnetic fields.2014

    • Author(s)
      Kojima S, Onishi H, et al.
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 8 Pages: 1-8

    • DOI

      10.3389/fnhum.2014.01023

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effect of the number of pins and inter-pin distance on somatosensory evoked magnetic fields following mechanical tactile stimulation.2013

    • Author(s)
      Onishi H, Sugawara K, , Yamashiro K, Sato D, Suzuki M, Kirimoto H, Tamaki H, Murakami H, Kameyama S.
    • Journal Title

      Brain Research

      Volume: 1535 Pages: 78-88

    • DOI

      10.1016/j.brainres.2013.08.048

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corticomotor excitability induced by anodal transcranial direct current stimulation with and without non-exhaustive movement.2013

    • Author(s)
      Miyaguchi S, Onishi H, Kojima S, Sugawara K, Tsubaki A, Kirimoto H, Tamaki H, Yamamoto N.
    • Journal Title

      Brain Research

      Volume: 1529 Pages: 83-91

    • DOI

      10.1016/j.brainres.2013.07.026

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Cortical activation following passive finger movements.2016

    • Author(s)
      Onishi H.
    • Organizer
      93rd Annual meeting of Physiological Science
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-22
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 短時間末梢神経刺激が体性感覚誘発磁界に及ぼす影響2015

    • Author(s)
      大西秀明,菅原和広,小丹晋一,山代幸哉,佐藤大輔,桐本光,田巻弘之, 丸山敦夫,白水洋史,亀山茂樹
    • Organizer
      第45 回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 体性感覚系の変化関連応答2015

    • Author(s)
      山代幸哉,佐藤大輔,大西秀明,菅原和広,下門洋文,中澤翔,白水洋史, 亀山茂樹,丸山敦夫
    • Organizer
      第45 回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 間欠的機械的触覚刺激による介入が皮質脊髄路興奮性に及ぼす影響2015

    • Author(s)
      小島翔,大西秀明,他
    • Organizer
      第45 回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 非筋疲労課題によるPost-exercise depression期間中の求心性抑制の変化2015

    • Author(s)
      宮口翔太,大西秀明,他
    • Organizer
      第45 回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 短時間末梢神経電気刺激が一次運動野の興奮性に与える影響2015

    • Author(s)
      小丹晋一,大西秀明,他
    • Organizer
      第45 回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 混合神経および指神経に対する電気刺激が皮質脊髄路の興奮性に与える影響2015

    • Author(s)
      佐々木亮樹,大西秀明,他
    • Organizer
      第45 回日本臨床神経生理学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 脳活動の検出と解析-脳磁図・近赤外線分光法・経頭蓋磁気刺激の応用-2015

    • Author(s)
      大西秀明
    • Organizer
      日本生体応用計測研究会第10回研究大会
    • Place of Presentation
      郡山(福島)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Effect of transcranial direct current stimulation on corticomotor excitability during active and passive finger movement.2015

    • Author(s)
      Onishi H, Miyaguchi S, Kirimoto H, Suzuki M.
    • Organizer
      International Conference on Complex Medical Engineering (CME 2015)
    • Place of Presentation
      Okayama, Japan
    • Year and Date
      2015-06-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 単発条件刺激が体性感覚誘発磁界に及ぼす影響2015

    • Author(s)
      大西秀明,菅原和広,小丹晋一,宮口翔太,小島翔,田巻弘之,白水洋史,亀山茂樹
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 他動運動時の運動範囲および運動速度が体性感覚誘発磁界に及ぼす影響2015

    • Author(s)
      菅原和広,大西秀明,他
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 筋収縮が短潜時および長潜時求心性抑制に及ぼす影響2015

    • Author(s)
      小島 翔,大西秀明,他
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 非筋疲労課題における運動時間が Post-exercise depression に与える影響2015

    • Author(s)
      宮口翔太,大西秀明,他
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 短時間末梢神経電気刺激による皮質脊髄路興奮性の変化2015

    • Author(s)
      小丹晋一,宮口翔太,小島翔,菅原和広,大西秀明
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 高頻度条件刺激が体性感覚誘発磁界に及ぼす影響2014

    • Author(s)
      大西秀明,菅原和広,小島翔,宮口翔太,小丹晋一,椿淳裕,山代幸哉,佐藤大輔,桐本光,田巻弘之,白水洋史,亀山茂樹.
    • Organizer
      第44回日本臨床神経生理学会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] 末梢感覚入力方法の違いが短潜時求心性抑制に及ぼす影響.2014

    • Author(s)
      小島 翔,大西秀明,小丹晋一,宮口翔太,菅原和広,桐本 光,田巻弘之,大高洋平.
    • Organizer
      第44回日本臨床神経生理学会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-19 – 2014-11-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] 短時間末梢神経刺激による体性感覚誘発磁界の変動2014

    • Author(s)
      大西秀明,菅原和広,小丹晋一,宮口翔太,小島翔,椿淳裕,田巻弘之,白水洋史,亀山茂樹.
    • Organizer
      日本基礎理学療法学会第4回学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-11-15 – 2014-11-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 末梢神経電気刺激による皮質運動野興奮性の変動‐刺激間隔および刺激回数による影響‐.2014

    • Author(s)
      宮口翔太,大西秀明,小島 翔,菅原和広,椿 淳裕,高井遥菜,松本卓也,桐本 光,田巻弘之.
    • Organizer
      第49回日本理学療法学会学術大会
    • Place of Presentation
      神奈川
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Annual Research Report
  • [Presentation] 電気刺激列による刺激条件が体性感覚誘発磁界に及ぼす影響2014

    • Author(s)
      大西秀明,菅原和広,宮口翔太,小島 翔,田巻弘之,桐本 光,山代幸哉,佐藤大輔,白水洋史,亀山茂樹.
    • Organizer
      第29回日本生体磁気学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-29 – 2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] Modulation of somatosensory evoked magnetic fields by the inter-stimulus interval of interfering stimuli.2014

    • Author(s)
      Onishi H, Sugawara K, Miyaguchi S, Kojima S, Tsubaki A, Tamaki H, Suzuki M, Kirimoto H, Yamashiro K, Sato D, Maruyama A, Shirozu H, Kameyama S.
    • Organizer
      30th International Congress of Clinical Neurophysiology (ICCN 2013)
    • Place of Presentation
      Berlin, Germany
    • Related Report
      2013 Annual Research Report
  • [Presentation] 正中神経連発刺激による体性感覚誘発磁界-連発刺激間隔による影響-2013

    • Author(s)
      大西秀明,菅原和広,小島 翔,宮口翔太,田巻弘之,桐本 光,鈴木 誠,山代幸哉,佐藤大輔,白水洋史,亀山茂樹.
    • Organizer
      第43回日本臨床神経生理学会
    • Place of Presentation
      高知市(高知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 機械的触覚刺激時の刺激ピン間隔と脳磁界反応について2013

    • Author(s)
      大西秀明,菅原和広,山代幸哉,佐藤大輔,鈴木誠,桐本 光,田巻弘之,村上博淳,亀山茂樹.
    • Organizer
      第48回日本理学療法学術大会
    • Place of Presentation
      名古屋市(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Book] Clinical Applications of Magnetoencephalography2016

    • Author(s)
      Onishi H and Kameyama S
    • Total Pages
      330
    • Publisher
      Springer
    • Related Report
      2015 Annual Research Report
  • [Book] 感覚入力で挑む2016

    • Author(s)
      大西秀明
    • Total Pages
      253
    • Publisher
      文光堂
    • Related Report
      2015 Annual Research Report
  • [Remarks] 新潟医療福祉大学運動機能医科学研究所

    • URL

      http://www.ihmms.jp/

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
  • [Remarks] Institute for Human movement and Medical Sciences

    • URL

      http://www.ihmms.jp/english/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 運動機能医科学研究所

    • URL

      http://www.ihmms.jp/

    • Related Report
      2013 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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